Evaluation of the performance of deformable image registration between planning CT and CBCT images for the pelvic region: comparison between hybrid and intensity-based DIR.
Evaluation of the performance of deformable image registration between planning CT and CBCT images for the pelvic region: comparison between hybrid and intensity-based DIR.
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评估骨盆区域的计划CT和CBCT图像之间可变形图像注册的性能：基于混合和强度的DIR之间的比较。
DOI：
10.1093/jrr/rrw123
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发表时间：
2017-07-01
影响因子：
2
通讯作者：
Jingu K
中科院分区：
文献类型：
--
作者：
Takayama Y;Kadoya N;Yamamoto T;Ito K;Chiba M;Fujiwara K;Miyasaka Y;Dobashi S;Sato K;Takeda K;Jingu K
本研究旨在评估混合变形图像配准（DIR）方法的性能，比较基于强度的骨盆锥形束计算机断层扫描（CBCT）图像的DIR，使用强度和解剖信息。本文对10例接受调强放疗的前列腺癌患者进行了研究。每位患者进行了9或10次CBCT扫描。首先，使用黄金基准标记将计划CT与所有CBCT图像进行刚性配准，然后进行DIR。采用Dice相似系数（DSC）和质心位移（COM）来评价定量DIR的精度。基于强度的前列腺、直肠、膀胱和精囊DIR的平均dsc分别为0.84±0.05、0.75±0.05、0.69±0.07和0.65±0.11，而混合DIR的dsc分别为0.98±0.00、0.97±0.01、0.98±0.00和0.94±0.03 （P < 0.05）。基于强度的前列腺、直肠、膀胱和精囊的平均COM位移分别为2.0±1.5、3.7±1.4、7.8±2.2和3.6±1.2 mm，而混合DIR的平均COM位移分别为0.1±0.0、0.3±0.2、0.2±0.1和0.6±0.6 mm （P < 0.05）。这些结果表明，与基于强度的DIR相比，混合DIR的DSC在所有结构和所有患者中都具有更高的DSC值和更小的COM位移。因此，基于混合DIR的累积剂量可作为一种考虑治疗放疗过程中器官运动的高精度剂量估计方法。
This study aimed to evaluate the performance of the hybrid deformable image registration (DIR) method in comparison with intensity-based DIR for pelvic cone-beam computed tomography (CBCT) images, using intensity and anatomical information. Ten prostate cancer patients treated with intensity-modulated radiation therapy (IMRT) were studied. Nine or ten CBCT scans were performed for each patient. First, rigid registration was performed between the planning CT and all CBCT images using gold fiducial markers, and then DIR was performed. The Dice similarity coefficient (DSC) and center of mass (COM) displacement were used to evaluate the quantitative DIR accuracy. The average DSCs for intensity-based DIR for the prostate, rectum, bladder, and seminal vesicles were 0.84 ± 0.05, 0.75 ± 0.05, 0.69 ± 0.07 and 0.65 ± 0.11, respectively, whereas those values for hybrid DIR were 0.98 ± 0.00, 0.97 ± 0.01, 0.98 ± 0.00 and 0.94 ± 0.03, respectively (P < 0.05). The average COM displacements for intensity-based DIR for the prostate, rectum, bladder, and seminal vesicles were 2.0 ± 1.5, 3.7 ± 1.4, 7.8 ± 2.2 and 3.6 ± 1.2 mm, whereas those values for hybrid DIR were 0.1 ± 0.0, 0.3 ± 0.2, 0.2 ± 0.1 and 0.6 ± 0.6 mm, respectively (P < 0.05). These results showed that the DSC for hybrid DIR had a higher DSC value and smaller COM displacement for all structures and all patients, compared with intensity-based DIR. Thus, the accumulative dose based on hybrid DIR might be trusted as a high-precision dose estimation method that takes into account organ movement during treatment radiotherapy.
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DOI：
10.1016/s0360-3016(00)00608-8
发表时间：
2000-08-01
影响因子：
7
作者：
Yan, D;Lockman, D;Martinez, A
通讯作者：
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DOI：
10.1016/j.ijrobp.2010.05.008
发表时间：
2011-03-01
影响因子：
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