The key role of zinc in elderly immunity: A possible approach in the COVID-19 crisis
The key role of zinc in elderly immunity: A possible approach in the COVID-19 crisis
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DOI：
10.1016/j.clnesp.2020.06.003
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发表时间：
2020-08-01
影响因子：
3
通讯作者：
Brasiel, Poliana Guiomar de Almeida
中科院分区：
文献类型：
--
作者：
Brasiel, Poliana Guiomar de Almeida
背景和目标：COVID-19感染可导致严重急性呼吸综合征冠状病毒2（SARS-CoV-2），主要影响60岁及以上的患者。初步数据表明，营养状况可以改变感染的过程，就这一点而言，锌对生长、发育和维持免疫功能至关重要。在缺乏对这种病毒的治疗的情况下，迫切需要找到有助于控制疾病的替代方法。本文的目的是建立锌和COVID-19之间的关系。方法和结果：根据现有的科学知识，我们对文献进行了回顾，并检查了锌在COVID-19感染中免疫功能的作用。我们的研究结果是，锌作为抗炎剂可能有助于优化免疫功能，降低感染风险。结论：补充锌可以是一种有效的策略，以减少全球老年人的感染负担，有必要增加报告，以提高我们对COVID-19的了解和对受影响患者的护理。(c)2020年欧洲临床营养与代谢学会。由爱思唯尔有限公司出版。保留所有权利。
Background & aims: The COVID-19 infection can lead to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), mainly affecting patients aged 60 and older. Preliminary data suggest that the nutritional status can change the course of the infection, and on the matter, zinc is crucial for growth, development, and the maintenance of immune function. In the absence of treatment for this virus, there is an urgent need to find alternative methods that can contribute to control of disease. The aim of this paper is to establish the relation between zinc and COVID-19.Methods and results: From the prior scientific knowledge, we have performed a review of the literature and examine the role of zinc in immune function in the infection by COVID-19. Our findings are that the zinc as an anti-inflammatory agent may help to optimize immune function and reduce the risk of infection.Conclusions: Zinc supplementation can be a useful strategy to reduce the global burden of infection in the elderly, there is a need the increased reporting to improve our understanding of COVID-19 and the care of affected patients. (c) 2020 European Society for Clinical Nutrition and Metabolism. Published by Elsevier Ltd. All rights reserved.