Basic Science Methods for Clinical Researchers

Basic Science Methods for Clinical Researchers
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发表时间:
2017
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通讯作者:
M. Jalali
M. Jalali
中科院分区:
其他
文献类型:
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作者:
M. Jalali

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临床研究人员的基础科学方法解决了没有传统科学背景的临床医生面临的具体挑战。本书的目的是向读者介绍核心实验方法,通常用于回答基础科学研究中的问题,并概述它们在生成结论性数据方面的相对优势和局限性。这本书将是一个重要的伙伴,临床医生承担实验室为基础的科学。它将支持临床医生追求他们的学术兴趣,并在他们选择的领域做出原创性贡献。在这样做的过程中,它将促进未来临床科学家和未来发现科学领导者的发展。为缺乏传统科学背景的临床研究人员提供有用的指导,围绕与关键生物分子有关的研究主题组织,从基因到蛋白质,细胞和模式生物。特征协议,解决常见问题的技术,并解释了生成结论性数据的技术的优点和局限性。附录提供了实用研究方法的资源。包括在实验室中使用干细胞和动物的法律框架、伦理考虑和良好实验室规范(GLP)
Basic Science Methods for Clinical Researchers addresses the specific challenges faced by clinicians without a conventional science background. The aim of the book is to introduce the reader to core experimental methods commonly used to answer questions in basic science research and to outline their relative strengths and limitations in generating conclusive data. This book will be a vital companion for clinicians undertaking laboratory-based science. It will support clinicians in the pursuit of their academic interests and in making an original contribution to their chosen field. In doing so, it will facilitate the development of tomorrow's clinician scientists and future leaders in discovery science. Serves as a helpful guide for clinical researchers who lack a conventional science background Organized around research themes pertaining to key biological molecules, from genes, to proteins, cells, and model organisms Features protocols, techniques for troubleshooting common problems, and an explanation of the advantages and limitations of a technique in generating conclusive data Appendices provide resources for practical research methodology, including legal frameworks for using stem cells and animals in the laboratory, ethical considerations, and good laboratory practice (GLP)