Topical epinephrine therapy of open-angel glaucoma.
Topical epinephrine therapy of open-angel glaucoma.
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开角型青光眼的局部肾上腺素治疗。
DOI：
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发表时间：
1961
期刊：
影响因子：
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通讯作者：
A. Gay
中科院分区：
文献类型：
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作者：
B. Becker;T. H. Pettit;A. Gay
在过去的十年中，人们对外用肾上腺素治疗青光眼重新产生了兴趣。更频繁地使用眼角膜检查来区分开角和闭角型青光眼是更好地定义肾上腺素使用的一个重要因素。张力图和荧光素转换研究提供了一些关于这种作用模式的见解，以及用于治疗青光眼的其他药物。1951年，Goldmann 1从荧光素转换研究中得出结论，葡聚糖通过减少房水分泌来降低眼压。Weekers， Prijot和Gustin，对14例眼压小于34 mm的慢性单纯性青光眼患者进行了研究。研究结果表明，局部肾上腺素在使用后48小时内可降低眼压，但不会改变眼球流出的功能。然而，在第二组7例患者中，张力大于35mm。汞，他们发现局部肾上腺素
The last decade has seen renewed interest in topical epinephrine for the treatment of glaucoma. The more frequent use of the gonioprism to distinguish open-angle from angle-closure glaucoma has been an important factor in better defining the use of epinephrine. Tonography and fluorescein-turnover studies have provided some insight into the mode of action of this as well as other agents used in the treatment of glaucoma. In 1951 Goldmann 1 concluded from fluorescein-turnover studies that glaucosan decreased intraocular pressure by decreasing the secretion of aqueous humor. Weekers, Prijot, and Gustin, 2 in a series of 14 patients with chronic simple glaucoma and pressures less than 34 mm. Hg, demonstrated tonographically that topical epinephrine lowered intraocular pressure in the first 48 hours of its use without altering the facility of outflow. In a second group of 7 patients, however, with tensions greater than 35 mm. Hg, they found that topical epinephrine