Performance evaluation of a subset of a four-layer LSO detector for a small animal DOI PET scanner: jPET-RD
Performance evaluation of a subset of a four-layer LSO detector for a small animal DOI PET scanner: jPET-RD
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DOI：
10.1109/tns.2005.862961
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发表时间：
2006-03
影响因子：
1.8
通讯作者：
T. Tsuda;H. Murayama;K. Kitamura;N. Inadama;T. Yamaya;E. Yoshida;F. Nishikido;M. Hamamoto;H. Kawai;Y. Ono
中科院分区：
文献类型：
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作者：
T. Tsuda;H. Murayama;K. Kitamura;N. Inadama;T. Yamaya;E. Yoshida;F. Nishikido;M. Hamamoto;H. Kawai;Y. Ono
在此之前，我们提出了一种新的相互作用深度（DOI）编码方法，并证明了它成功地与四层Gd/sub 2/SiO/sub 5/晶体的小动物正电子发射断层扫描（PET）探测器。我们现在正计划开发一种小动物PET扫描仪，jPET-RD（用于啮齿动物的DOI探测器），通过使用具有32/spl倍/32/spl倍/4晶体阵列的DOI探测器，该扫描仪具有高分辨率和高灵敏度。探测器的闪烁体为Lu/sub 2（1-x）/Y/sub 2x/SiO/sub 5/（LYSO）。在这项工作中，我们评估了DOI探测器的性能组成的四层的12/spl倍/12 LYSO（Lu：98%，Y：2%）晶体阵列均匀照射511 keV的伽马射线。新的编码方法用于晶体鉴定。每个晶体的尺寸为1.46 mm/spl times/1.46 mm/spl times/4.5 mm。将晶体块耦合到256通道平板位置敏感光电倍增管，该光电倍增管具有16/spl times/16个多阳极，间隔为3.04 mm。正如我们所预期的，所有晶体都表示在单个二维位置直方图上，没有重叠。FWHM的能量分辨率为21.8%，时间分辨率为0.69ns。从上到下依次计算，第一、二、三和四层事件的能量分辨率分别为11.6%、12.3%、13.3%和19.1%，时间分辨率分别为0.60ns、0.59ns、0.60ns和0.66ns。
Previously, we proposed a new depth of interaction (DOI) encoding method and proved that it worked successfully with four-layered Gd/sub 2/SiO/sub 5/ crystals for a small animal positron emission tomography (PET) detector. We are now planning to develop a small animal PET scanner, jPET-RD (for rodents with DOI detectors), which has both high resolution and high sensitivity by the use of a DOI detector with a 32/spl times/32/spl times/4 crystal array. The scintillator for the detector will be Lu/sub 2(1-x)/Y/sub 2x/SiO/sub 5/ (LYSO). In this work, we evaluated performance of a DOI detector composed of four layers of a 12/spl times/12 LYSO (Lu: 98%, Y: 2%) crystal array by irradiating 511 keV gamma rays uniformly. The new encoding method was used for crystal identification. The size of each crystal was 1.46 mm/spl times/1.46 mm/spl times/4.5 mm. The crystal block was coupled to a 256-channel flat panel position sensitive photomultiplier tube, which has 16/spl times/16 multi anodes at intervals of 3.04 mm. As we expected, all crystals are expressed on a single two-dimensional position histogram without overlapping. Energy resolution of all events is 21.8% and time resolution of all events is 0.69 ns in FWHM. When layers are counted from the top, the energy resolutions of the first, second, third, and fourth layer events are 11.6%, 12.3%, 13.3%, and 19.1% and the time resolutions are 0.60ns, 0.59ns, 0.60ns, and 0.66ns, respectively.