At What Age Do Children Start Taking Daily Asthma Medicines on Their Own?

At What Age Do Children Start Taking Daily Asthma Medicines on Their Own?
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DOI:
10.1542/peds.2008-0292
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发表时间:
2008-12-01
期刊:
影响因子:
8
通讯作者:
Cabana, Michael D.
Cabana, Michael D.
中科院分区:
医学2区
文献类型:
--
作者:
Orrell-Valente, Joan K.;Jarlsberg, Leah G.;Cabana, Michael D.

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OBJECTIVE.使用日常控制药物是持续性哮喘管理的关键任务。研究的目的是检查(1)在4至19岁的样本中,儿童年龄与每日服药责任程度之间的关系,(2)儿童每日服药责任和总体每日服药依从性的父母、儿童和疾病预测因素,以及(3)儿童每日服药责任和总体每日服药依从性之间的关系。我们进行了一项横断面电话调查的351名家长的儿童谁是处方每日控制药物。儿童的平均年龄为10.4岁; 61.5%为男性,88.1%为白色。父母提供了所有的数据,包括估计的百分比的儿童和父母的日常药物治疗的责任。每日服药依从性的测量方法是父母报告的典型一周内每剂处方药每日服用剂量的百分比。我们使用多元线性回归来确定父母种族/民族、教育、收入、受抚养人数、儿童年龄、性别、自诊断以来的年数、父母对症状严重程度和控制的感知以及因变量(儿童每日服药责任和每日服药依从性)之间的关联。我们还研究了儿童每日服药责任和每日服药依从性之间的关系。儿童每日控制用药的责任随着年龄的增长而增加。到7岁时,儿童平均承担了近20%的日常药物治疗责任;到11岁,接近50%;到15岁,75%;到19岁,100%。在多变量模型中,儿童年龄和男性性别与儿童每日服药责任显著相关,儿童年龄和父母种族/民族与每日服药依从性显著相关。临床医生可能需要筛查儿童日常用药管理,甚至在教育家庭使用哮喘药物和其他关键哮喘管理任务时也包括年幼的儿童。儿科2008; 122:e1186-e1192
OBJECTIVE. Use of daily controller medications is a critical task in management of persistent asthma. Study aims were to examine (1) the association between child age and extent of daily controller-medication responsibility in a sample aged 4 to 19 years, (2) parent, child, and disease predictors of child daily controller-medication responsibility and overall daily controller-medication adherence, and (3) the association between child daily controller-medication responsibility and overall daily controller-medication adherence.METHODS. We conducted a cross-sectional telephone survey of 351 parents of children who were prescribed daily controller medication. Children's mean age was 10.4 years; 61.5% were male, and 88.1% were white. Parents provided all data, including an estimate of the percentage of child and parent daily controller-medication responsibility. Daily controller-medication adherence was measured as parents' report of percentage of daily doses taken per doses prescribed in a typical week. We used multivariate linear regression to determine associations between parent race/ethnicity, education, income, number of dependents, child age, gender, years since diagnosis, parent perception of symptom severity and control, and dependent variables (child daily controller-medication responsibility and daily controller-medication adherence). We also examined associations between child daily controller-medication responsibility and daily controller-medication adherence.RESULTS. Child daily controller-medication responsibility increased with age. By age 7, children had assumed, on average, almost 20% of daily controller-medication responsibility; by age 11, similar to 50%; by age 15, 75%; and by age 19, 100%. In multivariate models, child age and male gender remained significantly associated with child daily controller-medication responsibility, and child's age and parents' race/ethnicity remained significantly associated with daily controller-medication adherence.CONCLUSIONS. Clinicians may need to screen for child daily controller-medication management and include even young children when educating families on the use of asthma medications and other key asthma-management tasks. Pediatrics 2008; 122: e1186-e1192