Intraoperative microelectrode and semi-microelectrode recording during the physiological localization of the thalamic nucleus ventral intermediate
Intraoperative microelectrode and semi-microelectrode recording during the physiological localization of the thalamic nucleus ventral intermediate
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DOI：
10.1002/mds.10155
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发表时间：
2002-01-01
影响因子：
8.6
通讯作者：
Lenz, FA
中科院分区：
文献类型：
--
作者：
Garonzik, IM;Hua, SE;Lenz, FA
我们回顾了正中腹侧（Vim）丘脑切开术或植入正中腹侧-深部脑刺激（DBS）治疗帕金森性、原发性和意向性震颤的生理定位技术。综述了微电极和半微电极技术。我们相信使用微电极和半微电极记录结合放射标志提供最准确的目标定位。除了记录外，通过微电极微刺激皮层下结构，如Vim和丘脑尾侧腹核，可以分别通过改变震颤和唤起躯体感觉来改善生理识别。微电极记录以增加定位目标的时间为代价，提供了目标部位的大7最佳分辨率图像。我们也回顾了丘脑神经元放电与震颤时肌电活动之间的关系。这些结果对帕金森病机制的影响。讨论了本质震颤和意图震颤。(C) 2002运动障碍学会。
We review the techniques of physiological localization of the site for ventralis intermedius (Vim) thalamotomy or implantation of Vim-deep brain stimulation (DBS) for treatment of parkinsonian, essential, and intention tremor. Both microelectrode and semi-microelectrode techniques are reviewed. We believe the use of microelectrode and semi-microelectrode recordings in combination with Radiological landmarks provide the most accurate localization of the target. In addition to recording, microstimulation of subcortical structures such as Vim and thalamic nucleus ventralis caudal through the microelectrode may improve physiological identification by altering the tremor and evoking somatic sensations, respectively. Microelectrode recording provides the big 7 best resolution picture of the target site at a cost of increased time to locate the target. We also review the relationship between thalamic neuronal firing and electromyographic activity during tremor. Implications of these results for the mechanisms for parkinsonian. essential, and intention tremors are discussed. (C) 2002 Movement Disorder Society.