Quantitative analysis of functional clustering of neurons in the macaque inferior temporal cortex
Quantitative analysis of functional clustering of neurons in the macaque inferior temporal cortex
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DOI：
10.1016/j.neures.2005.04.006
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发表时间：
2005-08-01
影响因子：
2.9
通讯作者：
Fujita, I
中科院分区：
文献类型：
--
作者：
Tamura, H;Kaneko, H;Fujita, I
对中等复杂度的二维形状具有相似偏好的神经元聚集在猴子下颞叶皮层的TE区。为了进一步表征TE区的功能结构，我们在麻醉猴中应用多个单单位记录技术定量分析了近距离神经元视觉反应的各个方面。检查的视觉反应引起的一个大的，预定的视觉刺激证实了以前的发现，附近的神经元，平均而言，表现出正相关的偏好一组视觉刺激。附近的神经元在感受场组织和对比极性偏好方面也趋于相似。相比之下，没有相关性被发现在相邻神经元的大小调谐。如果一对附近的神经元分别具有正相关或负相关的刺激偏好，则将一对附近的神经元之间的活动合并或减去可以提高刺激的可辨别性。这些结果表明，附近的TE神经元共享刺激偏好的某些方面，但它们的反应选择性在其他方面有所不同。如果将这些解码策略应用于适当的神经元池，则附近神经元之间的池化和减法都可以减少跨试验响应的变异性。(c)2005年Elsevier爱尔兰有限公司和日本神经科学学会。All rights reserved.
Neurons with similar preferences for two-dimensional shapes of intermediate complexity cluster in area TE of the monkey inferior temporal cortex. To further characterize the functional structure of area TE, we quantitatively analyzed various aspects of the visual responses of closely located neurons by applying multiple single-unit recording techniques in anesthetized monkeys. Examination of the visual responses elicited with a large, predetermined set of visual stimuli confirmed previous findings that nearby neurons, on average, exhibited positively correlated preferences for a set of visual stimuli. Nearby neurons also tended to be similar in their receptive-field organization and contrast-polarity preference. In contrast, no correlation was found in the size tuning of neighboring neurons. Pooling or subtraction of activities between a pair of nearby neurons was shown to improve stimulus discriminability, if the neuron pair had positively or negatively correlated stimulus preferences, respectively. These results indicate that nearby TE neurons share some aspects of stimulus preference, but their response selectivity differ in other aspects. Both pooling and subtraction between nearby neurons can reduce across-trial response variability, if these decoding strategies are applied to appropriate neuronal pools. (c) 2005 Elsevier Ireland Ltd and the Japan Neuroscience Society. All rights reserved.