Comparison of thick blood smear and saponin haemolysis for the detection of Loa loa and Mansonella perstans infections.
Comparison of thick blood smear and saponin haemolysis for the detection of Loa loa and Mansonella perstans infections.
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厚血涂片和皂苷溶血检测 Loa loa 和 Mansonella perstans 感染的比较。
DOI：
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发表时间：
1990
期刊：
影响因子：
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通讯作者：
J. D. Apembet
中科院分区：
文献类型：
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作者：
F. Noireau;J. D. Apembet
在某流行地区，若采用常规的2次厚血涂片（40微升血）诊断为微丝虫病，则检出罗阿罗氏菌和曼索菌，检出率分别为7.4%和26.2%。为了接近真实的寄生虫流行率，对厚血膜所得结果进行校正的因子为L. loa为1.5，M. perstans为1.6。此外，对大容量血液的分析可以更好地估计被寄生群体的微丝虫负荷。
In an endemic area, Loa loa and Mansonella perstans microfilariae were detected by the examination of 5 ml blood in respectively 7.4 and 26.2% of subjects who would have been erroneously considered amicrofilaraemic by the conventional method of two thick blood smears (40 microliters blood). Correction factors to be applied to the results obtained with thick blood films in order to approach the true parasitological prevalences were 1.5 for L. loa and 1.6 for M. perstans. In addition, the analysis of a large volume of blood provides a better estimation of microfilarial load of the parasitized population.