Pathogenicity islands: the tip of the iceberg
Pathogenicity islands: the tip of the iceberg
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DOI：
10.1016/s1286-4579(01)01410-1
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发表时间：
2001-06-01
影响因子：
5.8
通讯作者：
Hacker, J
中科院分区：
文献类型：
--
作者：
Hentschel, U;Hacker, J
致病岛代表了编码致病细菌毒力因子的不同遗传元件。致病岛属于基因组岛的一类，它们是共享一组统一特征的常见遗传元件。基因组岛是通过水平基因转移获得的。近年来，在各种致病细菌和非致病细菌中发现了许多不同的基因组岛。因为它们促进了遗传多样性，基因组岛在微生物进化中扮演着重要的角色。(C)2001年版《爱思唯尔科学与医学》。
Pathogenicity islands represent distinct genetic elements encoding virulence factors of pathogenic bacteria. Pathogenicity islands belong to the class of genomic islands, which are common genetic elements sharing a set of unifying features. Genomic islands have been acquired by horizontal gene transfer. In recent years many different genomic islands have been discovered in a variety of pathogenic as well as non-pathogenic bacteria. Because they promote genetic variability, genomic islands play an important role in microbial evolution. (C) 2001 Editions scientifiques et medicales Elsevier SAS.