Effects of replacing the habitual consumption of sugar-sweetened beverages with milk in Chilean children
Effects of replacing the habitual consumption of sugar-sweetened beverages with milk in Chilean children
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DOI：
10.1093/ajcn/88.3.605
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发表时间：
2008-09-01
影响因子：
7.1
通讯作者：
Ludwig, David S.
中科院分区：
文献类型：
--
作者：
Albala, Cecilia;Ebbeling, Cara B.;Ludwig, David S.
背景：在智利的营养转型期间，饮食变化的特点是高能量、低营养产品的消费增加，包括含糖饮料（SSB）。肥胖现在是转型后智利的主要营养问题。目的：我们进行了一项随机对照试验，以检查向超重和肥胖儿童的家中提供牛奶饮料以取代 SSB 对身体成分的影响。设计：我们将 98 名经常食用 SSB 的 8-10 岁儿童随机分为干预组和对照组。在为期 16 周的干预中，儿童被要求每天喝 3 份（每份约 200 克）送到家中的牛奶，并且不要食用 SSB。通过双能X射线吸收法测量身体成分。根据意向治疗原则对数据进行多元回归分析。结果：干预组的牛奶消耗量平均 (+/- SEM) 增加了 452.5 +/- 37.7 g/d (P < 0.0001)，SSB 消耗量减少了 -711.0 +/- 33.7 g/d (P < 0.0001)。对于对照组，牛奶消耗量没有变化，SSB 的消耗量增加了 71.9 +/- 33.6 g/d (P = 0.04)。主要终点——体脂百分比的变化在各组之间没有差异。然而，干预组的去脂体重平均（+/- SE）增加（0.92 +/- 0.10 kg）高于对照组（0.62 +/- 0.11 kg）（P = 0.04）。男孩的身高增加（2.50 +/- 0.21 厘米）也比对照组（1.77 +/- 0.20 厘米）更大（P = 0.01），但女孩则不然。结论：尽管体脂百分比没有变化，但用牛奶代替习惯性食用的 SSB 可能对儿童的去脂体重和生长产生有益影响。该试验在 ClinicalTrials.gov 上注册为 NCT00149695。
Background: During the nutrition transition in Chile, dietary changes were marked by increased consumption of high-energy, nutrient-poor products, including sugar-sweetened beverages (SSBs). Obesity is now the primary nutritional problem in posttransitional Chile. Objective: We conducted a randomized controlled trial to examine the effects on body composition of delivering milk beverages to the homes of overweight and obese children to displace SSBs. Design: We randomly assigned 98 children aged 8-10 y who regularly consumed SSBs to intervention and control groups. During a 16-wk intervention, children were instructed to drink 3 servings/d (approximate to 200 g per serving) of the milk delivered to their homes and to not consume SSBs. Body composition was measured by dual-energy X-ray absorptiometry. Data were analyzed by multiple regression analysis according to the intention-to-treat principle. Results: For the intervention group, milk consumption increased by a mean (+/- SEM) of 452.5 +/- 37.7 g/d (P < 0.0001), and consumption of SSBs decreased by -711.0 +/- 33.7 g/d (P < 0.0001). For the control group, milk consumption did not change, and consumption of SSBs increased by 71.9 +/- 33.6 g/d (P = 0.04). Changes in percentage body fat, the primary endpoint, did not differ between groups. Nevertheless, the mean (+/- SE) accretion of lean body mass was greater (P = 0.04) in the intervention (0.92 +/- 0.10 kg) than in the control (0.62 +/- 0.11 kg) group. The increase in height was also greater (P = 0.01) in the intervention group (2.50 +/- 0.21 cm) than in the control group (1.77 +/- 0.20 cm) for boys but not for girls. Conclusion: Replacing habitual consumption of SSBs with milk may have beneficial effects on lean body mass and growth in children, despite no changes in percentage body fat. This trial was registered at clinicaltrials.gov as NCT00149695.