No tDCS augmented working memory training benefit in undergraduates rewarded with course credit
No tDCS augmented working memory training benefit in undergraduates rewarded with course credit
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DOI：
10.1016/j.brs.2020.08.015
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发表时间：
2020-09
影响因子：
7.7
通讯作者：
Jorja Shires;Carlos Carrasco;M. Berryhill
中科院分区：
文献类型：
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作者：
Jorja Shires;Carlos Carrasco;M. Berryhill
工作记忆（WM）训练的目标是扩展这一执行功能的能力。经颅直流电刺激（tDCS）与WM训练相结合比单独使用更具有一致性。我们已经报道了针对额叶和/或顶叶区域的tDCS增强了theta相锁定，降低了alpha功率，并加强了theta-gamma相振幅耦合。目的确定tDCS额叶或顶叶网站优化WM培训收益我们预注册tDCS-WM培训学习。方法80名大学生随机分为四组：额叶（F4）、顶叶（P4）、交替（P4 - F4）和假（P4或F4）。参与者在一周内完成了5次培训，并在30天无接触后返回进行随访测试。结果两组在训练结束及随访时均无明显改善。结论：这一无效发现标志着在本科生训练中观察到的研究生训练的益处无法复制。我们认为，动机是必不可少的，以提高训练协议的性能。
BackgroundThe goal of working memory (WM) training is to expand capacity of this executive function. Transcranial direct current stimulation (tDCS) paired with WM training is more consistent than either alone. We have reported that tDCS targeting frontal and/or parietal regions enhanced theta phase locking, reduced alpha power, and strengthened theta-gamma phase amplitude coupling.ObjectiveTo determine whether tDCS to frontal or parietal sites optimized WM training gains we pre-registered a tDCS-WM training study.Methods80 undergraduates were randomly assigned to one of four anodal tDCS montages: frontal (F4), parietal (P4), alternating (P4–F4), and sham (P4 or F4). Participants completed 5-training sessions over one week and returned for follow-up testing after 30 days of no-contact.ResultsNo group showed significant improvement in trained or transfer task performance at the end of training nor at follow-up.ConclusionsThis null finding marks a failure to replicate in undergraduates training benefits observed in graduate students. We argue that motivation is essential to elicit improved performance in training protocols.