THE FIMA GENE ENCODING THE TYPE-1 FIMBRIAL SUBUNIT OF ESCHERICHIA-COLI - NUCLEOTIDE-SEQUENCE AND PRIMARY STRUCTURE OF THE PROTEIN

THE FIMA GENE ENCODING THE TYPE-1 FIMBRIAL SUBUNIT OF ESCHERICHIA-COLI - NUCLEOTIDE-SEQUENCE AND PRIMARY STRUCTURE OF THE PROTEIN
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DOI:
10.1111/j.1432-1033.1984.tb08386.x
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发表时间:
1984-01-01
期刊:
EUROPEAN JOURNAL OF BIOCHEMISTRY
影响因子:
--
通讯作者:
KLEMM, P
KLEMM, P
中科院分区:
其他
文献类型:
--
作者:
KLEMM, P

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测定了大肠杆菌1型菌毛亚单位fimA基因及其两侧包含潜在调控序列的区域共1450个碱基对的核苷酸序列。翻译得到的蛋白质包含一个23个残基的信号肽;加工后的菌毛亚单位由158个氨基酸残基组成,相对分子质量为15706。所阐明的序列与其他大肠杆菌菌毛蛋白的序列具有显著的同源性。
The nucleotide sequence was determined of a region of 1450 base pairs encompassing the fimA gene for the subunit of type 1 fimbriae of E. coli as well as flanking regions containing potential regulator sequences. The translated protein contains a 23-residue signal peptide; the processed fimbrial subunit consists of 158 amino acid residues yielding a relative molecular mass of 15,706. The elucidated sequence shows significant homology with those of other E. coli fimbrial proteins.