MR imaging of the skin and nipple of the breast: differentiation between tumour recurrence and post-treatment change
MR imaging of the skin and nipple of the breast: differentiation between tumour recurrence and post-treatment change
复制标题
乳房皮肤和乳头的 MR 成像：肿瘤复发和治疗后变化的区别
DOI：
10.1007/s003300100837
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发表时间：
2001
影响因子：
5.9
通讯作者：
C. Saunders
中科院分区：
文献类型：
--
作者：
G. Ralleigh;A. Walker;M. Hall;S. Lakhani;C. Saunders
对比增强的MR成像的乳房已被发现是有价值的评估局部复发的先前治疗的乳腺癌。我们特别观察了治疗乳房的皮肤和乳头的外观，以描述该区域治疗后变化和复发的外观。39名接受乳腺癌治疗的女性对一侧或双侧乳房进行了回顾性MR成像，特别注意乳头和皮肤。对乳房切除术患者的皮肤和胸壁进行评估。对MR成像后获得的所有可用的皮肤和/或乳头组织学进行了审查。在MR成像后未接受手术的患者中，获得了临床随访。39例中有6例在MR成像上看到结节状增强区，这与组织学显示皮肤和/或乳头内肿瘤复发相关。其余33例患者中，15例患者的皮肤和/或乳头出现线性或弥漫性强化改变。在4例病例中，这些变化在手术/活检时显示为良性治疗后变化，其余病例在临床随访时显示为良性治疗后变化。在这篇文章中，我们展示了复发性乳腺癌与治疗后变化的皮肤和乳头内对比增强的不同模式。这表明，对比增强的乳腺磁共振成像可能是一个有用的工具，在区分肿瘤复发治疗后的皮肤和乳头内的变化。
Contrast-enhanced MR imaging of the breast has been found to be valuable in the assessment of local recurrence of previously treated breast cancer. We looked specifically at the appearances of the skin and nipple of the treated breast in order to describe the appearances of post-treatment change and recurrence in this region. Thirty-nine women treated for breast cancer had MR imaging of one or both breasts reviewed retrospectively with particular attention to the nipple and skin. The skin and chest wall were assessed for patients with mastectomies. All available histology of the skin and/or nipple, obtained following MR imaging, was reviewed. In patients who did not undergo surgery following MR imaging, clinical follow-up was obtained. Six of 39 cases had nodular enhancing areas seen on MR imaging, which correlated with histology demonstrating tumour recurrence within the skin and/or nipple. Of the remaining 33 patients, changes of linear or diffuse enhancement were seen in the skin and/or nipple of 15 patients. These changes were shown to be benign post-treatment changes at surgery/biopsy in 4 cases or by clinical follow-up in the remainder. In this article we demonstrate differing patterns of contrast enhancement within the skin and nipple in recurrent breast carcinoma vs post-treatment changes. This suggests that contrast-enhanced MR imaging of the breast may be a useful tool in differentiating tumour recurrence from post-treatment changes within the skin and nipple.