Comparison between peak expiratory flow and FEV1 measurements on a home spirometer and on a pneumotachograph in children with asthma
Comparison between peak expiratory flow and FEV1 measurements on a home spirometer and on a pneumotachograph in children with asthma
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DOI：
10.1002/ppul.20660
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发表时间：
2007-09-01
影响因子：
3.1
通讯作者：
Brand, Paul L. P.
中科院分区：
文献类型：
--
作者：
Brouwer, Alwin F. J.;Roorda, Ruurd Jan;Brand, Paul L. P.
背景：电子便携式家用肺活量计的准确性已在体外使用基于计算机的波形得到证实。我们评估了电子肺量计（Koko Peak Pro）肺功能测量值与医院肺功能实验室呼吸速度描记器金标准肺功能测量值之间的体内一致性。研究方法：对50例6-17岁稳定期哮喘儿童（33例男孩），根据国际指南，随机采用便携式家用肺量计和医院呼吸速度描记器进行呼气峰流速（PEF）和一秒用力呼气量（FEV 1）测定。所有测量均符合标准质量标准。比较家庭肺量计和医院呼吸速度描记器记录的PEF和FEV值。结果：所有儿童在两种肺量计上进行了可重复的高质量测量。家用肺量计的PEF值显著低于实验室呼吸速度描记器（PEF差异的95% CI为14-30 L/min; P <100 L/min）。家用肺量计的FEV 1值略低，但具有显著性（FEV 1差异的95% CI为0.02-0.1 L; P <0.0018）。结论：当在专业监督和鼓励下进行时，家用肺量计为哮喘儿童提供了可重复和质量可接受的测量。家用肺量计记录的平均PEF和FEV值明显低于医院呼吸速度描记器记录的值，个体差异可能很大。因此，在肺功能实验室中，家庭肺功能测定法不能与呼吸速度描记法互换。
Background: The accuracy of electronic portable home spirometers has been demonstrated in vitro using computer-based waveforms. We assessed the agreement in vivo between measurements of lung function on an electronic spirometer (Koko Peak Pro) and those obtained by the gold standard, a hospital lung function laboratory pneumotachograph. Methods: Fifty stable asthmatic children (33 boys), aged 6-17 years, performed peak expiratory flow (PEF) and forced expiratory volume in 1 see (FEV1) measurements according to international guidelines on a portable home spirometer and on the hospital pneumotachograph in random order. All measurements complied to standard quality criteria. The PEF and FEV, values recorded with the home spirometer and on the hospital pneumotachograph were compared. Results: All children performed reproducible high-quality measurements on both spirometers. PEF values on the home spirometer were considerably lower than on the laboratory pneumotachograph (95% CI for difference in PEF 14-30 L/min; P100 L/min. The FEV1 values were slightly, but significantly, lower on the home spirometer (95% CI for difference in FEV1 0.02-0.1 L; P 0.0018). Conclusions: A home spirometer provides reproducible and quality acceptable measures in children with asthma when performed under professional supervision and encouragement. Mean PEF and FEV, values recorded on this home spirometer are significantly lower than those on a hospital pneumotachograph, and individual differences may be large. Therefore, home spirometry may not be interchanged with pneumotachography in a lung function laboratory.