Polymorphisms in cytomegalovirus genotype in immunocompetent patients with corneal endotheliitis or iridocyclitis
Polymorphisms in cytomegalovirus genotype in immunocompetent patients with corneal endotheliitis or iridocyclitis
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DOI：
10.1002/jmv.24239
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发表时间：
2015-08-01
影响因子：
12.7
通讯作者：
Ohashi, Yuichi
中科院分区：
文献类型：
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作者：
Oka, Naoko;Suzuki, Takashi;Ohashi, Yuichi
对免疫功能正常的患者中引起角膜内皮炎和虹膜睫状体炎的巨细胞病毒（CMV）进行基因分型。在7例内皮炎和5例虹膜睫状体炎中检测到gB 1型（77.8%和100%），在2例内皮炎中检测到gB 3型（22.2%）。在5例内皮炎样本（45.5%）和5例虹膜睫状体炎样本（83.3%）中发现UL 144 1型。在两个内皮炎样本（18.2%）和一个虹膜睫状体炎样本（16.7%）中发现UL 144 2型。内皮炎和虹膜睫状体炎以gB 1型为主，内皮炎和虹膜睫状体炎的CMV基因型相似。医学病毒学杂志87：1441-1445，2015. (c)2015 Wiley Periodicals，Inc.
Cytomegalovirus (CMV) that caused corneal endotheliitis and iridocyclitis in immunocompetent patients was genotyped. The gB type1 was detected in seven endotheliitis samples (77.8%) and five iridocyclitis samples (100%), and the gB type 3 was detected in two endotheliitis samples (22.2%). The UL144 type 1 was found in five endotheliitis samples (45.5%) and five iridocyclitis samples (83.3%). The UL144 type 2 was found in two endotheliitis samples (18.2%) and one iridocyclitis sample (16.7%). The gB type 1 was predominant in endotheliitis and iridocyclitis, and the CMV genotypes in eyes with endotheliitis and iridocyclitis were similar. J. Med. Virol. 87:1441-1445, 2015. (c) 2015 Wiley Periodicals, Inc.