Guidelines for the retention, storage, and use of residual dried blood spot samples after newborn screening analysis: Statement of the Council of Regional Networks for Genetic Services
Guidelines for the retention, storage, and use of residual dried blood spot samples after newborn screening analysis: Statement of the Council of Regional Networks for Genetic Services
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DOI：
10.1006/bmme.1996.0017
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发表时间：
1996-04-01
期刊：
影响因子：
--
通讯作者：
Shapira, E
中科院分区：
文献类型：
--
作者：
Therrell, BL;Hannon, WH;Shapira, E
这些指南为国家卫生部门在筛查测试完成后考虑适当使用新生儿筛查标本的政策制定提供了科学信息，信息被收集、辩论并由区域遗传服务网络委员会（CORN）的新生儿筛查委员会制定为政策声明，该委员会是一个由联邦政府资助的由10个区域遗传网络代表组成的国家联盟。新生儿筛查方案在收集用于新生儿筛查的残余干血斑样本（DBS）的方法和政策方面差异很大。人们认识到DBS样本在艾滋病毒血清患病率调查中的流行病学效用，以及对DBS用于DNA分析的兴趣日益浓厚，这加强了对残余DBS样本的保留、储存和使用问题的考虑。这些样本有可能为全国所有新生儿提供一个遗传物质“库”。科学家、管理人员和司法官员已经认识到它们作为其他用途的资源的价值。各项目应根据科学有效的信息颁布保留和使用剩余新生儿筛查DBS样本的规则。应根据对社会的潜在利益或危害来考虑将新生儿样本作为遗传物质来源。(C) 1996学术出版社，Inc.
These guidelines provide scientific information for policy development by state health departments considering appropriate use of newborn screening specimens after screening tests are finished, Information was collected, debated, and formulated into a policy statement by the Newborn Screening Committee of the Council of Regional Networks for Genetic Services (CORN), a federally funded national consortium of representatives from 10 regional genetics networks. Newborn screening programs vary widely in approaches and policies concerning residual dried blood spot samples (DBS) collected for newborn screening. Recognition of the epidemiological utility of DBS samples for HIV seroprevalence surveys and a growing interest in DBSs for DNA analysis has intensified consideration of issues regarding retention, storage, and use of residual DBS samples. Potentially these samples provide a genetic material ''bank'' for all newborns nationwide. Their value as a resource for other uses has already been recognized by scientists, administrators, and judicial officials, Programs should promulgate rules for retention and use of residual newborn screening DBS samples based on scientifically valid information. Banking of newborn samples as sources of genetic material should be considered in light of potential benefit or harm to society. (C) 1996 Academic Press, Inc.