MicroRNA482/2118, a miRNA superfamily essential for both diseaseresistance and plant development
MicroRNA482/2118, a miRNA superfamily essential for both diseaseresistance and plant development
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DOI：
10.1111/nph.17853
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发表时间：
2021
期刊：
影响因子：
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通讯作者：
Rui Xia
中科院分区：
文献类型：
--
作者：
Yanqing Zhang;Muhammad Waseem;Zaohai Zeng;Jing Xu;Chengjie Chen;Yuanlong Liu;Jixian Zhai;Rui Xia
MicroRNAs (miRNAs) are a class of 21–24 nucleotides (nt) noncoding small RNAs ubiquitouslydistributed across the plant kingdom. miR482/2118, one of the conserved miRNA superfamiliesoriginating from gymnosperms, has divergent main functions in core-angiosperms. It mainlyregulatesNUCLEOTIDE BINDING SITE-LEUCINE-RICH REPEAT(NBS-LRR) genes in eudicots,functioning as an essential component in plant disease resistance; in contrast, it predominantlytargets numerous long noncoding RNAs (lncRNAs) in monocot grasses, which are vital for plantreproduction. Usually, miR482/2118 is 22-nt in length, which can trigger the production ofphased small interfering RNAs (phasiRNAs) after directed cleavage. PhasiRNAs instigated fromtarget genes of miR482/2118 enhance their roles in corresponding biological processes bycis-regulation on cognate genes and expands their function to other pathways viatransactivity ondifferent genes. This review summarizes the origin, biogenesis, conservation, and evolutionarycharacteristics of the miR482/2118 superfamily and delineates its diverse functions in diseaseresistance, plant development, stress responses, etc.
