Acceptability of Human Papillomavirus Self-Sampling Among a National Sample of Women in the United States
Acceptability of Human Papillomavirus Self-Sampling Among a National Sample of Women in the United States
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DOI：
10.1089/biores.2018.0040
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发表时间：
2019-04-30
影响因子：
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通讯作者：
Reiter, Paul L.
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文献类型：
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作者：
Bishop, Erin;Katz, Mira L.;Reiter, Paul L.
随着人乳头瘤病毒（HPV）自我采样在美国继续成为一种潜在的宫颈癌筛查策略，有必要检查女性对这种筛查方法的接受程度。此外，由于存在多种 HPV 自采样设备，因此确定女性的偏好是否因设备类型而异非常重要。我们于 2017 年秋季对全国 21-65 岁（宫颈癌筛查的推荐年龄范围）女性样本 (n=605) 进行了一项在线调查。多变量线性回归确定了女性在家中使用 HPV 自我样本意愿的相关性。我们使用重复测量方差分析来确定四种自采样设备的偏好是否不同：Evalyn((R)) Brush（设备 A）、HerSwab((R))（设备 B）、Catch-All((R)) Swab（设备 C）和 Qvintip((R))（设备 D）。大多数女性愿意在家中使用 HPV 自我样本（平均值 = 4.03 [可能范围：1-5]，标准差 = 1.09，72.7% 表示可能愿意或绝对愿意）。对自采样最常见的担忧与测试准确性（53.1%）和样本获取不正确（51.1%）有关。如果女性报告自己的宫颈癌严重程度较高 (=0.16)、年收入低于 50,000 美元 (=0.13) 或曾经吸烟过 (=0.11)，则她们更愿意在家中使用 HPV 自我样本。与设备 B（平均值 = 3.36，49.4% 表示同意或强烈同意）相比，女性更愿意使用设备 A（平均值 = 3.72，67.6% 表示同意或强烈同意）、设备 C（平均值 = 3.86，73.9% 表示同意或强烈同意）和设备 D（平均值 = 3.81，72.1% 表示同意或强烈同意）
As human papillomavirus (HPV) self-sampling continues to emerge as a potential cervical cancer screening strategy in the United States, it is necessary to examine women's acceptability of this screening approach. Furthermore, since several HPV self-sampling devices exist, it is important to determine if women's preferences differ by device type. We conducted an online survey in Fall 2017 with a national sample of women (n=605) ages 21-65 years (the recommended age range for cervical cancer screening). Multivariable linear regression identified correlates of women's willingness to use an HPV self-sample at home. We used repeated measures analysis of variance to determine if preferences differed across four self-sampling devices: Evalyn((R)) Brush (Device A), HerSwab((R)) (Device B), Catch-All((R)) Swab (Device C), and Qvintip((R)) (Device D). Most women were willing to use an HPV self-sample at home (mean=4.03 [possible range: 1-5], standard deviation=1.09, 72.7% indicated probably willing or definitely willing). The most common concerns about self-sampling were related to test accuracy (53.1%) and obtaining the sample incorrectly (51.1%). Women were more willing to use an HPV self-sample at home if they reported greater perceived severity of cervical cancer (=0.16), reported an annual income less than $50,000 (=0.13), or were a former smoker (=0.11). Women were more willing to use Device A (mean=3.72, 67.6% indicated agree or strongly agree), Device C (mean=3.86, 73.9% indicated agree or strongly agree), and Device D (mean=3.81, 72.1% indicated agree or strongly agree) than Device B (mean=3.36, 49.4% indicated agree or strongly agree; all p