The predictive value of total serum IgE for a positive allergen specific IgE result
The predictive value of total serum IgE for a positive allergen specific IgE result
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DOI：
10.1136/jcp.2004.017681
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发表时间：
2004-09-01
影响因子：
3.4
通讯作者：
Peters, SA
中科院分区：
文献类型：
--
作者：
Sinclair, D;Peters, SA
背景：血清总IgE和过敏原特异性IgE的测量通常被要求评估可能的过敏。随着公众意识的提高，过敏评估的要求也在增加;除非有明确的“过敏原嫌疑人”，否则可能会提出几个过敏原特异性IgE要求。这增加了检测到相关性不确定的过敏原特异性IgE临界增加的可能性，并且对服务具有重要的成本影响。目的：为这一观察提供证据基础。在这项回顾性观察研究中，从2001年3月至2003年2月，对301名16岁以下的患者进行了“过敏试验”。结果：过敏原特异性IgE检测在低血清总IgE浓度儿童中的应用（
Background: Measurement of total serum IgE and allergen specific IgE is often requested to assess possible allergy. As public awareness increases, so do requests for allergy assessment; unless there is a clear "allergen suspect'' in the history, several allergen specific IgE requests may be made. This increases the likelihood of detecting borderline increases in allergen specific IgE of uncertain relevance, and has important cost implications for the service.Aims: To provide an evidence base for this observation.Methods: In this retrospective observational study, results from 301 patients under 16 years of age from whom blood was taken for "allergy testing'' from March 2001 to February 2003 were studied.Results: Allergen specific IgE testing in children with low total serum IgE concentrations (