19-YEAR INCIDENCE OF NEURAL TUBE DEFECTS IN AREA UNDER CONSTANT SURVEILLANCE
19-YEAR INCIDENCE OF NEURAL TUBE DEFECTS IN AREA UNDER CONSTANT SURVEILLANCE
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持续监测区域神经管缺陷 19 年发病率
DOI：
10.1016/s0140-6736(81)91226-5
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发表时间：
1981
期刊：
影响因子：
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通讯作者：
L. West
中科院分区：
文献类型：
--
作者：
J. Owens;E. Mcallister;F. Harris;L. West
1961年至1979年对利物浦和布托地区神经管缺陷的流行病学研究表明，从1974年开始呈下降趋势。这一趋势非常显著，无脑儿比脊柱裂更明显。从1977年到1979年，17例因神经管缺陷而终止妊娠，但这个数字太小了，不能对发病率产生明显的影响。没有任何单一因素可以解释这一观察结果。
A study of the epidemiology of neural tube defects in the Liverpool and Bootle areas between 1961 and 1979 showed a decline from 1974 onwards. This trend was highly significant and was more marked for anencephaly than for spina bifida. From 1977 to 1979, seventeen pregnancies were terminated for neural tube defects, but this number was too small to have an appreciable effect on incidence. No single factor can be implicated to explain this observation.