THE RELAPSES OF CYSTIC ACNE AFTER ISOTRETINOIN TREATMENT ARE AGE-RELATED - A LONG-TERM FOLLOW-UP-STUDY
THE RELAPSES OF CYSTIC ACNE AFTER ISOTRETINOIN TREATMENT ARE AGE-RELATED - A LONG-TERM FOLLOW-UP-STUDY
复制标题
DOI：
10.1159/000249320
复制
发表时间：
1986-03-01
期刊：
影响因子：
--
通讯作者：
RADEFF, B
中科院分区：
文献类型：
--
作者：
HARMS, M;MASOUYE, I;RADEFF, B
用异维A酸治疗重度痤疮89例，男66例，女23例，随访6-47个月，平均14个月。复发率为14.6%。未发现其与异维甲酸给药总量（高达233 mg/kg）相关;由于16.6%的雄性和8.6%的雌性发生复发，因此观察到可能与性别相关（尽管不显著）。但是患者的年龄对复发的可能性有很大的影响：年轻患者比老年患者更容易复发。
89 patients (66 males and 23 females) with severe acne were treated with isotretinoin and were followed up for a period of 6-47 months (mean 14 months) after the end of the therapy. Relapses occurred in 14.6% of the patients. They were not found to be related to the total amount of isotretinoin administered (up to 233 mg/kg); a possible, although not significant, link to sex was observed since relapses occurred in 16.6% males and 8.6% of females. But the age of the patients had a significant bearing on the likelihood of relapses: younger patients relapsed more frequently than older patients.