Antibiotics in Dutch general practice: nationwide electronic GP database and national reimbursement rates
Antibiotics in Dutch general practice: nationwide electronic GP database and national reimbursement rates
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DOI：
10.1002/pds.1501
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发表时间：
2008-04-01
影响因子：
2.6
通讯作者：
van Dijk, Liset
中科院分区：
文献类型：
--
作者：
Akkerman, Annemiek E.;Kuyvenhoven, Mariike M.;van Dijk, Liset
目的 为了评估不同数据库是否生成相互比较可靠的信息，本研究旨在评估全国电子全科医生 (GP) 数据库中的全身抗生素处方率与国家报销率的对应程度，并调查抗生素的处方适应症。 方法 全国全科医生处方数据来自第二次荷兰全科医学全国调查 (DNSGP-2) 基于 2001 年为 358 008 名患者提供服务的 90 个全科诊所。荷兰国家全科医生报销率源自 2001 年荷兰药品信息系统/医疗保险委员会 (GIP/CVZ) 的索赔数据。我们计算了每个数据库每 1000 名患者/居民的抗生素处方率，并将这些比率与总比率和抗生素亚组进行比较。描述了全科医生开抗生素的适应症。结果在国家报销数据中，全科医生开出了每1000名居民339张抗生素处方，而全国全科医生数据库显示每1000名患者有255张抗生素处方（报销率覆盖率为75%）。全国全科医生数据库显示大量磺胺类药物和甲氧苄啶，以及少量大环内酯类和喹诺酮类药物。一半 (48%) 的处方用于呼吸系统疾病，四分之一 (26%) 用于泌尿系统疾病，7% 用于耳部疾病。 结论 自愿参与研究网络的全科医生开出的抗生素总体少于荷兰全科医生，并且在开出更新、更广谱的抗生素时持谨慎态度。当数据库相互比较时必须考虑这一点。版权所有 (c) 2007 John Wiley & Sons, Ltd.
Purpose In order to assess whether different databases generate information which can be reliable compared with each other, this study aimed to assess to which degree prescribing rates for systemic antibiotics from a nationwide electronic general practitioner (GP) database correspond with national reimbursement rates, and to investigate for which indications antibiotics are prescribed.Methods Nationwide GP prescribing data were collected from the Second Dutch National Survey of General Practice (DNSGP-2) based on 90 general practices serving 358 008 patients in 2001. Dutch national reimbursement rates for GPs were derived from claims data of the Dutch Drug Information System/Health Care Insurance Board (GIP/CVZ) from 2001. We calculated antibiotic prescribing rates per 1000 patients/inhabitants for each database, and these rates were compared for the total rates and according to antibiotic subgroups. Indications for which GPs prescribed antibiotics were described.Results In national reimbursement data, 339 antibiotic prescriptions per 1000 inhabitants were prescribed by GPs, while the nationwide GP database showed 255 prescriptions per 1000 patients (75% coverage with reimbursement rates). The nationwide GP database showed high volumes of sulphonamides & trimethoprim, and small volumes of macrolides and quinolones. Half of the prescriptions (48%) were prescribed for respiratory diseases, a quarter (26%) for urinary diseases and 7% for ear diseases.Conclusions GPs voluntarily participating in a research network prescribe less antibiotics than Dutch GPs in general, and are cautious in prescribing newer and more broad-spectrum antibiotics. This point has to be taken into account when databases will be compared with each other. Copyright (c) 2007 John Wiley & Sons, Ltd.