Impact of atrial fibrillation on mortality, stroke, and medical costs
Impact of atrial fibrillation on mortality, stroke, and medical costs
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DOI：
10.1001/archinte.158.3.229
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发表时间：
1998-02-09
影响因子：
--
通讯作者：
D'Agostino, RB
中科院分区：
文献类型：
--
作者：
Wolf, PA;Mitchell, JB;D'Agostino, RB
背景资料：房颤（AF）对死亡率、卒中和医疗费用的影响尚不清楚。我们进行了一项前瞻性队列研究，将患有AF和1种其他心血管诊断（CVD）的住院医疗保险患者与无AF的匹配组进行比较（n=26 753），在6个年龄段随机选择-1989年MedPAR文件中超过100万被诊断为AF的患者的性别分层。在另一个无CVD的队列中也确定了卒中发生率（n=14 267）。从1991年的队列中获得了住院后的总医疗费用。累积死亡率，中风率，指数入院后的成本进行了调整，多变量和比例风险回归analysis.Results：死亡率高，在个人与心血管疾病，范围从19.0%至52.1%，在1年。在3年的研究中，所有年龄-性别分层的AF患者校正的相对死亡风险约高20%（P
Background: The impact of atrial fibrillation (AF) on mortality, stroke, and medical costs is unknown.Methods: We conducted a prospective cohort study of hospitalized Medicare patients with AF and 1 other cardiovascular diagnosis (CVD) compared with a matched group without AF (n=26 753), randomly selected in 6 age-sex strata from 1989 MedPAR files of more than 1 million patients diagnosed as having AF. Stroke rates were also determined in another cohort free of CVD (n=14 267). Total medical costs after hospitalization were available from a 1991 cohort. Cumulative mortality, stroke rates, and costs following index admission were adjusted by multivariate and proportional hazard regression analyses.Results: Mortality rates were high in individuals with CVD, ranging from 19.0% to 52.1% in 1 year. Adjusted relative mortality risk was approximately 20% higher in patients with AF in all age-sex strata during each of the 3 years studied (P