Irreversible intestinal failure: Prevalence and prognostic factors
Irreversible intestinal failure: Prevalence and prognostic factors
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DOI：
10.1097/mpg.0b013e31817af979
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发表时间：
2008-10-01
影响因子：
2.9
通讯作者：
Gambarara, Manuela
中科院分区：
文献类型：
--
作者：
Diamanti, Antonella;Basso, Maria Sole;Gambarara, Manuela
背景和目的：肠外营养（PN）是肠衰竭的主要治疗方法，肠衰竭在部分或完全依赖PN的患者中被认为是不可逆的。不可逆性肠衰竭的原因是短肠综合征（SBS）、动力障碍（MD）和严重迁延性腹泻（SPD）。本研究的目的是报告这些患者与基础疾病相关的临床结局。自1989年1月1日至2006年12月31日，我中心共观察了218例肠功能衰竭患者，（48例SBS、39例SPD和9例MD）入选，因为他们需要至少50%的总热量作为PN，持续时间不少于3个月。结果：SBS组的生存率明显高于其他组（P
Background and Aim: Parenteral nutrition (PN) is the primary treatment for intestinal failure, which is considered irreversible in patients who remain partially or fully dependent on PN. Causes of irreversible intestinal failure are short bowel syndrome (SBS), motility disorders (MD), and severe protracted diarrhea (SPD). The aim of this study was to report the clinical outcome in these patients in relation to the underlying disease.Patients and Methods: From January 1, 1989 to December 3 1, 2006, 218 intestinal failure patients were observed in our center, but only 96 (48 SBS, 39 SPD, and 9 MD) were included because they required at least 50% of their total calories as PN for not less than 3 months. In these patients, survival and complication rates were evaluated.Results: The survival rate was significantly higher in SBS patients than in the other groups (P