Survival and future need of long-term oxygen therapy for chronic obstructive pulmonary disease -: gender differences
Survival and future need of long-term oxygen therapy for chronic obstructive pulmonary disease -: gender differences
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DOI：
10.1016/j.rmed.2007.01.009
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发表时间：
2007-07-01
影响因子：
4.3
通讯作者：
Strom, Kerstin
中科院分区：
文献类型：
--
作者：
Franklin, Karl A.;Gustafson, Torbjorn;Strom, Kerstin
我们的目的是研究慢性阻塞性肺疾病长期氧疗的发病率和患病率的性别差异趋势。另一个目的是研究开始氧疗后的生存率。Prosthesis随访了5689名瑞典患者，这些患者在1987年至2000年期间因慢性阻塞性肺病接受氧疗。女性开始氧疗的年发病率比男性增加得更快。2000年，每100 000名妇女中有7.6人开始接受治疗，而男子为7.1人。在瑞典，在接受氧气的年龄组，即65-84岁的年龄组中，曾经吸烟的频率在妇女中为36.4%，在男子中为65.0%，这表明妇女患需要氧气的慢性低氧血症的风险更高。由于年轻和中年女性吸烟频率的增加，预计需要氧疗的女性将增加，预计到2026年，瑞典约70%的氧疗患者将是女性，估计患病率为61/100，000。总之，长期氧疗的发病率和患病率在女性中比男性增长更快。这可能是由于与男子相比，妇女吸烟的频率增加，以及妇女更容易患严重低氧血症。长期氧疗的女性生存率高于男性。(C)2007爱思唯尔有限公司保留所有权利。
We aimed to study trends in gender-related differences in incidence, and prevalence for tong-term oxygen therapy due to chronic obstructive pulmonary disease. Another aim was to study survival after onset of oxygen therapy.Prospectively followed were 5689 Swedish patients, who were prescribed oxygen therapy because of chronic obstructive pulmonary disease from 1987 to 2000.The annual incidence of women starting oxygen therapy increased more rapidly than that in men. In 2000, 7.6 per 100,000 women started treatment compared with 7.1 in men. The frequency of ever smoking in Sweden in the age group receiving oxygen, i.e. age 65-84 years, was 36.4% in women and 65.0% in men, indicating that women ran a higher risk of developing an oxygen-requiring chronic hypoxaemia. An increase in women requiring oxygen therapy is predicted due to the increase in smoking frequency in young and middle-aged women and it is estimated that about 70% of Swedish patients on oxygen in 2026 will be women, with an estimated prevalence of 61 per 100,000.In conclusion, the incidence and prevalence for tong-term oxygen therapy increases more rapidly among women than in men. This is probably due to the increased frequency of smoking in women compared with men and a higher susceptibility to develop severe hypoxaemia in women. The survival is better in women with long-term oxygen therapy than in men. (C) 2007 Elsevier Ltd. All rights reserved.