Lignins and Their Derivatives with Beneficial Effects on Human Health.
Lignins and Their Derivatives with Beneficial Effects on Human Health.
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DOI：
10.3390/ijms18061219
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发表时间：
2017-06-07
影响因子：
5.6
通讯作者：
Mitjans M
中科院分区：
文献类型：
--
作者：
Vinardell MP;Mitjans M
对木质素药理应用的综述提供了其对不同疾病发展具有保护作用的证据。在很多情况下，木质素的作用可由其抗氧化能力来解释。在此，我们对2010 - 2016年期间的文献进行了系统综述，这些文献提供了有关近期研究中木质素新应用的信息。报告了最有前景的研究结果，包括所采用的方法以及使用木质素或其衍生物所获得的可能改善人类健康的结果。我们强调了其在肥胖症、糖尿病、血栓形成、病毒感染和癌症治疗中的潜在应用。此外，我们还报告了木质素可用于制备纳米颗粒以递送不同药物以及其在光保护方面的应用。
A review of the pharmacological applications of lignins provides evidence of their protective role against the development of different diseases. In many cases, the effects of lignins could be explained by their antioxidant capacity. Here, we present a systematic review of the literature from the period 2010–2016 which provides information concerning new applications of lignins derived from recent research. The most promising findings are reported, including the methodologies employed and results obtained with lignins or their derivatives which may improve human health. We highlight potential applications in the treatment of obesity, diabetes, thrombosis, viral infections and cancer. Moreover, we report both that lignins can be used in the preparation of nanoparticles to deliver different drugs and also their use in photoprotection.