Synthetic Glycopolymers: Some Recent Developments

Synthetic Glycopolymers: Some Recent Developments
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DOI:
10.1007/12_2013_254
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发表时间:
2013
期刊:
Proceedings of the National Academy of Sciences
影响因子:
--
通讯作者:
Qiang Zhang;D. Haddleton
Qiang Zhang;D. Haddleton
中科院分区:
其他
文献类型:
--
作者:
Qiang Zhang;D. Haddleton

文献摘要

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糖共聚物是含有糖部分的合成大分子。它们在生物相关的应用中显示出了希望,并且用于制造这些分子的合成方法的数量正在迅速扩大。这一领域得益于合成高分子化学的快速发展,在功能性糖基共聚物的合成方面取得了巨大进展。在糖共聚物合成中采用的策略通常作为糖单体的直接聚合或预形成的聚合物的后糖基化来进行。这一贡献是一个简短的概述,最近的一些发展,并希望引导读者到许多感兴趣的文件。
Glycopolymers are synthetic macromolecules containing sugar moieties. They have shown promise in biorelated applications and the number of synthetic approaches for making these molecules is expanding rapidly. This field benefits from the rapid development of synthetic polymer chemistry, which has seen dramatic progress in the synthesis of functional glycopolymers. Strategies employed in glycopolymer synthesis have been generally carried out as either direct polymerization of glycomonomers or post-glycosylation of pre-formed polymers. This contribution is a short overview of some of the recent developments and will hopefully direct the reader to many papers of interest.