Solitary capillary hemangioma of the lung - Report of 2 resected cases detected by high-resolution CT
Solitary capillary hemangioma of the lung - Report of 2 resected cases detected by high-resolution CT
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DOI：
10.1097/00000478-200606000-00012
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发表时间：
2006-06-01
影响因子：
5.6
通讯作者：
Moriyama, Noriyuki
中科院分区：
文献类型：
--
作者：
Fugo, Kazunori;Matsuno, Yoshihiro;Moriyama, Noriyuki
我们报告2例毛细血管瘤，每一个都表现为一个孤立的结节在周围肺。这两个病人都是无症状的小孤立结节，显示了计算机断层扫描。在这两种情况下，结节手术切除的临床诊断为早期肺癌。肉眼观察，每个病变边界不清，形状不规则，切面呈深棕色。显微镜下，两个结节中的肺泡隔因大量薄壁毛细血管的积聚而增厚，这些薄壁毛细血管的特征是沿着延伸或浸润每个隔。我们诊断这些病变为“孤立性毛细血管瘤”的周围肺。肺部毛细血管的肿瘤或肿瘤样病变很少见。其中，肺毛细血管瘤病（PCH）被描述为肺实质或支气管血管壁的多发性结节，由浸润的薄壁毛细血管组成。此外，在尸检病例的回顾性研究中发现了PCH样病灶。然而，本病例应根据其临床背景（如高血压或静脉闭塞性疾病史和病变的多样性）与PCH相鉴别。这是一个罕见的个案系列孤立毛细血管瘤偶然发现在生活中，病变是很难区分的放射线与早期肺癌。随着周围型肺癌早期影像学诊断的进步，这些病变在细支气管肺泡癌的鉴别诊断中是非常重要的。
We report 2 cases of capillary hemangioma, each presenting as a solitary nodule in the peripheral lung. Both of the patients were asymptomatic with a small solitary nodule that had revealed by computed tomography. In both cases, the nodule was resected surgically under a clinical diagnosis of early lung cancer. Macroscopically, each lesion was ill defined and irregular in shape with a dark brown cut surface. Microscopically, the alveolar septa in both nodules were thickened by accumulations of numerous thin-walled capillary vessels, which characteristically extended along, or infiltrated, each septum. We diagnosed these lesions as "solitary capillary hemangioma" of the peripheral lung. Tumors or tumorlike lesions of capillary vessels in the lung are rare. Among them, pulmonary capillary hemangiomatosis (PCH) has been described as multiple nodules in the lung parenchyma or bronchovascular walls, comprised of infiltrating thin-walled capillary blood vessels. Moreover, PCH-like foci have been found in a retrospective study of autopsy cases. However, the presented cases should be differentiated from PCH in terms of their clinical setting such as history of hypertension or veno-occlusive disease and multiplicity of the lesion. This is a rare case series of solitary capillary hemangioma discovered incidentally during life, and the lesions were difficult to differentiate radiologically from early lung cancer. After the recent advances in imaging diagnosis for early detection of peripheral lung cancer, these lesions are important to bear in mind for differential diagnosis of bronchioloalveolar carcinoma.