Perfluorooctanoate and perfluorooctane sulfonate concentrations in surface water in Japan
Perfluorooctanoate and perfluorooctane sulfonate concentrations in surface water in Japan
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DOI：
10.1539/joh.46.49
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发表时间：
2004-01-01
影响因子：
3
通讯作者：
Koizumi, A
中科院分区：
文献类型：
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作者：
Saito, N;Harada, K;Koizumi, A
全氟辛酸盐（PFOA）和全氟辛烷磺酸盐（PFOS）是日本使用的合成表面活性剂。对接触全氟辛酸的工人进行的一项流行病学研究显示，前列腺癌死亡率显著增加。一项对接触PFOA的工人的横断面研究表明，PFOA扰乱了性激素的稳态。我们分析了从日本各地收集的地表水样品中的浓度，通过LC/MS与固相萃取法。全氟辛酸和全氟辛烷磺酸的最低检测限（纳克/升）分别为0.06和0.04。两种分析物的最低定量限（LOQ）（ng/L）均为0.1。地表沃茨中全氟辛酸和全氟辛烷磺酸的水平[几何平均值（GM）;几何标准差（GS）]（纳克/升）为GM（GS）：0.97（3.06）和1.19北海道-东北（n=16）为2.44;（3.56）和3.69关东地区（n=14）为3.93;（2.23）和1.07中部组（n=17）为2.36;（2.28）和5.73（3.61）; 1.51（2.28）和1.00（3.42）中国（n=9）; 1.93（2.40）和0.89（3.09）九州四国（n=15）。PFOA的GM在近畿地区显著高于其他地区（ANOVA p
Perfluorooctanoate (PFOA) and perfluorooctane sulfonate (PFOS) are synthetic surfactants used in Japan. An epidemiological study of workers exposed to PFOA revealed a significant increase in prostate cancer mortality. A cross-sectional study of PFOA-exposed workers showed that PFOA perturbs sex hormone homeostasis. We analyzed their concentrations in surface water samples collected from all over Japan by LC/MS with a solid phase extraction method. The lowest limits of detection (LOD) (ng/L) were 0.06 for PFOA and 0.04 for PFOS. The lowest limits of quantification (LOQ) (ng/L) were 0.1 for both analytes. The levels [geometric mean (GM); geometric standard deviation (GS)] (ng/L) of PFOA and PFOS in the surface waters were GM (GS): 0.97 (3.06) and 1.19 (2.44) for Hokkaido-Tohoku (n=16); 2.84(3.56) and 3.69 (3.93) for Kanto (n=14); 2.50 (2.23) and 1.07 (2.36) for Chubu (n=17); 21.5 (2.28) and 5.73 (3.61) for Kinki (n=8); 1.51 (2.28) and 1.00 (3.42) for Chugoku (n=9); 1.93 (2.40) and 0.89 (3.09) for Kyushu-Shikoku (n=15). The GM of PFOA in Kinki was significantly higher than in other areas (ANOVA p