Further eleganolone-derived diterpenes from the brown alga Bifurcaria bifurcata
Further eleganolone-derived diterpenes from the brown alga Bifurcaria bifurcata
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DOI：
10.1016/j.tetlet.2011.09.128
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发表时间：
2012-04-11
影响因子：
1.8
通讯作者：
Koeck, Matthias
中科院分区：
文献类型：
--
作者：
Goethel, Qun;Lichte, Ellen;Koeck, Matthias
从法国罗斯科夫附近海域采集的棕色双叉叉藻中分离到4个新的二萜类化合物（1-4）和6个已知的二萜类化合物。在1D和2D NMR光谱和质谱（ESI-MS）分析的基础上进行了全面的研究，确定了新化合物的结构。我们的分配支持的C-13 NMR化学位移的比较，已知的化合物和预测值。这些新的二萜是二萜eleganolone（5）的衍生物。讨论了新二萜类化合物（1-4）与已知二萜类化合物的结构关系和代谢途径。(C)2012爱思唯尔有限公司保留所有权利。
Four new diterpenes (1-4) together with six known members of this family were isolated from the brown alga Bifurcaria bifurcata collected off the coast near Roscoff, France. The structures of the new compounds were established in a comprehensive study on the basis of 1D and 2D NMR spectroscopic and mass spectrometric (ESI-MS) analyses. Our assignment is supported by a comparison of the C-13 NMR chemical shifts to known compounds and predicted values. The new diterpenes are derivatives of the diterpene eleganolone (5). The structural relation and hypothetical metabolic pathway of the new diterpenes (1-4) with the co-isolated known diterpenes are discussed. (C) 2012 Elsevier Ltd. All rights reserved.