No part may be reproduced by any process witnout written permission from the author(s) W4(4a) and W6(4b) in Diverse Human Populations. Demonstration of their Genetic Identity in Population and Segregation Studies

No part may be reproduced by any process witnout written permission from the author(s) W4(4a) and W6(4b) in Diverse Human Populations. Demonstration of their Genetic Identity in Population and Segregation Studies
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未经 Diverse Human Populations 作者 W4(4a) 和 W6(4b) 的书面许可,不得以任何方式复制任何部分。

DOI:
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发表时间:
1975
期刊:
影响因子:
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通讯作者:
J. Amaro
J. Amaro
中科院分区:
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文献类型:
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作者:
J. Amaro

文献摘要

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通过对200个荷兰家庭755名儿童的隔离和交配研究,重新评价了W4、W6系统与HL-A系统的关系。对第五次讲习班的人群进行了纳入分析,并与莱顿主要档案的参考分析相关。交配和分离分析结果表明,W4和W6作为一个遗传系统具有良好的拟合性。包含分析显示了高度的一致性。基于这些结果和其他引用的证据,我们认为W4和W6可能代表了FOUR系列HL-A抗原的基本物质。
The status of the W4, W6 system as related to the HL-A system was re-evaluated by means of segregation and mating studies in 200 Dutch families with 755 children. Inclusion analyses were performed on the Fifth Workshop human populations and related to a reference analysis on the main file in Leiden. The results of the mating and segregation analyses showed a good fit for W4 and W6 as a genetic system. The inclusion analyses showed a high degree of concordance. Based on those results, and other cited evidence, it was suggested that W4 and W6 may represent the basic substance of the HL-A antigens in the FOUR series.