Palladium-catalyzed C-H acetoxylation of 2-methoxyimino-2-aryl-acetates and acetamides.
Palladium-catalyzed C-H acetoxylation of 2-methoxyimino-2-aryl-acetates and acetamides.
复制标题
DOI：
10.1039/c1ob05887h
复制
发表时间：
2011-09
影响因子：
3.2
通讯作者：
Liang Wang;X. Xia;Wei Guo;Jia‐Rong Chen;W. Xiao
中科院分区：
文献类型：
--
作者：
Liang Wang;X. Xia;Wei Guo;Jia‐Rong Chen;W. Xiao
研究了钯催化的2-甲氧基亚氨基-2-芳基乙酸酯和乙酰胺的C-H乙酰氧基化反应。这些转化具有优异的区域选择性、宽的底物范围和中等至良好的产率。该产品可以很容易地转化为天然前所未有的α-氨基酸，产率很高。
Palladium-catalyzed C-H acetoxylation reactions of 2-methoxyimino-2-aryl-acetates and acetamides have been developed. These transformations feature excellent regioselectivity, wide substrate scope, and moderate to good yields. The product can be easily converted into naturally unprecedented α-amino acids in excellent yields.