Effect of functional shift of the mandible on lubrication of the temporomandibular joint
Effect of functional shift of the mandible on lubrication of the temporomandibular joint
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DOI：
10.1016/j.archoralbio.2012.01.006
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发表时间：
2012-07-01
影响因子：
3
通讯作者：
Ono, Takashi
中科院分区：
文献类型：
--
作者：
Kure-Hattori, Ikuko;Watari, Ippei;Ono, Takashi
滑膜关节的润滑降低了摩擦系数。关节软骨表面。为了研究咬合不正对颞下颌关节（TMJ）润滑的影响，我们在下颌骨功能性侧移条件下，在生长期，通过免疫组织化学方法评估了大鼠 TMJ 中润滑素的表达。 30只5周龄雄性Wistar大鼠分为实验组、恢复组和对照组。实验组和恢复组中的每个房间都配备了丙烯酸板导向装置。实验组和对照组的大鼠在安装装置后14天和28天处死。恢复组中的每只大鼠在第14天时脱离矫治器，并在移除矫治器14天后处死。在实验组中，实验期间TMJ软骨中lubricin染色的表达显着降低。恢复组TMJ软骨中lubricin染色表达量显着高于实验组，且28天时对照组与恢复组无显着性差异。对这些数据的分析表明，下颌骨在生长期的功能性侧移会影响颞下颌关节的润滑。 (C) 2012 Elsevier Ltd. 保留所有权利。
Lubrication of synovial joints reduces the coefficient of friction. of the articular cartilage surface. To investigate the effect of malocclusion on the lubrication of the temporomandibular joint (TMJ), we evaluated lubricin expression in the rat TMJ immunohistochemically, under conditions of functional lateral shift of the mandible, during period of growth. Thirty 5-week-old male Wistar rats were divided into experimental, recovery, and control groups. Each rt in the experimental and recovery groups was fitted with an acrylic-plate guiding appliance. The rats in the experimental and control groups were killed at 14 and 28 days after the appliance was attached. Each rat in the recovery group was detached from the appliance at 14 days, and was killed 14 days after the appliance was removed. In the experimental group, the expression of lubricin staining in TMJ cartilage was significantly decreased during the experimental period. In the recovery group, the expression of lubricin staining in TMJ cartilage was significantly greater than in the experimental group, and there was no significant difference at 28 days between the control and recovery groups. Analysis of these data suggests that a functional lateral shift of the mandible during the growth period influences lubrication of the TMJ. (C) 2012 Elsevier Ltd. All rights reserved.