Cyanobacteriochromes: a new superfamily of tetrapyrrole-binding photoreceptors in cyanobacteria
Cyanobacteriochromes: a new superfamily of tetrapyrrole-binding photoreceptors in cyanobacteria
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DOI：
10.1039/b802660m
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发表时间：
2008-10-01
影响因子：
3.1
通讯作者：
Ishizuka, Takami
中科院分区：
文献类型：
--
作者：
Ikeuchi, Masahiko;Ishizuka, Takami
在蓝藻中实验发现了一组新的光感受器。它们是趋光性调节子SyPixJ1、TePixJ和AnPixJ、显色驯化调节子SyCcaS、昼夜输入激酶同源物SyCikA和许多其他候选化合物，到目前为止只在蓝藻中发现。这些新的光感受器现在被认为是“蓝藻碘色素”。它们的特征是存在一个生色团结合的GAF结构域，该结构域与光敏色素的四吡咯结合的GAF结构域同源。在这里，我们总结了这些代表的独特特征：(1)只有GAF结构域足以进行完全的光转化，(2)GAF结构域与光敏色素GAF同源但不同，(3)GAF结构域结合线性四吡咯色素，如藻蓝胆素或藻蓝胆素，(4)从近紫外区到红区的光谱性质非常不同。我们还讨论了其他候选GAFs的功能、结构和进化。
A new group of photoreceptors has been experimentally revealed in cyanobacteria. They are phototaxis regulator SyPixJ1, TePixJ and AnPixJ, chromatic acclimation regulator SyCcaS, circadian input kinase homolog SyCikA and many other candidates, which have been found only in cyanobacteria to date. These new photoreceptors are now proposed to be "cyanobacteriochromes". They are characterized by the presence of a chromophore-binding GAF domain that is homologous to the tetrapyrrole-binding GAF domain of the phytochrome. Here, we summarized unique features of those representatives: (1) only the GAF domain is sufficient for full photoconversion, (2) the GAF domain is homologous to but distinct from the phytochrome GAF, (3) the GAF domain binds a linear tetrapyrrole pigment such as phycoviolobilin or phycocyanobilin, (4) spectral properties are very diverse from near ultra-violet to red region. We also discussed the functionality of the other candidate GAFs, structure and evolution.