A GPCR Handles Bacterial Sensing in Chemotaxis and Phagocytosis.
A GPCR Handles Bacterial Sensing in Chemotaxis and Phagocytosis.
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GPCR 处理趋化和吞噬作用中的细菌感应。
DOI:
10.1016/j.devcel.2016.02.006
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发表时间:
2016
影响因子:
11.8
通讯作者:
Iijima,Miho
中科院分区:
文献类型:
--
作者:
Senoo,Hiroshi;Sesaki,Hiromi;Iijima,Miho
In this issue ofDevelopmental Cell, Pan et al. (2016) identified in cells of the social amoebaDictyosteliuma G protein-coupled receptor (GPCR) that recognizes a chemoattractant secreted by bacteria. This work uncovers a mechanism by which a single GPCR mediates pseudopod extension during cell migration and bacterial engulfment.