House dust in seven Danish offices
House dust in seven Danish offices
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DOI：
10.1016/s1352-2310(00)00104-7
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发表时间：
2000-01-01
影响因子：
5
通讯作者：
Jorgensen, O
中科院分区：
文献类型：
--
作者：
Molhave, L;Schneider, T;Jorgensen, O
收集并分析了丹麦办公室的地板灰尘。这些灰尘将用于暴露实验。对粉尘进行了分析，以显示粉尘的成分，这可能是室内空气传播粉尘的来源。根据标准化程序处理了来自丹麦7座办公楼（约12751 m2）的真空吸尘器袋中的约11 kg粉尘，产生5.5kg经处理的散装粉尘。大量粉尘含有130.000-160.000 CFU g（-1）微生物和71.000-90.000 CFU g（-1）微真菌。30 g（-1）粉尘中可培养真菌的含量为65-123 CFU。内毒素含量范围为5.06-7.24 EU g（-1）（1.45 ng g（-1）-1.01 ng g（-1））。过敏原（ng/g）为147-159（螨）、395-746（犬）和103-330（猫）。大分子有机化合物（MOD含量）为7.8-9.8 mg g（-1）。由大量粉尘引起的嗜碱性白细胞释放组胺的阈值在0.3和1.0 mg ml（-1）之间。含水量为2%（WGT），有机部分为33%，6.5-5.9%（干）是水溶性的。纤维含量小于0.2-1.5%（WGT），可解吸的VOC为176-319 μ g g（-1）。大部分VOC为醛类，但存在塑料软化剂（DBP和DEHP）。化学成分包括人类和动物的皮肤碎片、纸纤维、玻璃棉、木材和纺织纤维以及无机和金属颗粒。粒径范围为0.001-1 mm，平均比重为1.0 g/m ~ 3。将大量粉尘重新悬浮并注入暴露室中。对空气中的灰尘进行了取样和分析，以说明沉淀的污垢和灰尘可能导致的暴露。由散尘产生的气载粉尘浓度范围为0.26-0.75 mg m（-3），平均含300-170 CFU m（-3）。有机部分为55-70%，水含量约2.5%（WGT）。粉尘的含量与文献中报道的类似结果进行了比较，估计其毒性相对较低。实验过程中粉尘的贮存对粉尘的生物和化学成分影响不大。(C)2000爱思唯尔科技有限公司版权所有。
Floor dust from Danish offices was collected and analyzed. The dust was to be used in an exposure experiment. The dust was analyzed to show the composition of the dust which can be a source of airborne dust indoors, About 11 kg of dust from vacuum cleaner bags from seven Danish office buildings with about 1047 occupants(12 751 m(2)) was processed according to a standardized procedure yielding 5.5kg of processed bulk dust. The bulk dust contained 130.000-160.000 CFU g(-1) microorganisms and 71.000-90.000 CFU g(-1) microfungi. The content of culturable microfungi was 65-123 CFU 30 g(-1) dust. The content of endotoxins ranged from 5.06-7.24 EU g(-1) (1.45 ng g(-1) to 1.01 ng g(-1)). Allergens (ng g(-1)) were from 147-159 (Mite), 395-746 (dog) and 103-330 (cat). The macro molecular organic compounds (the MOD-content) varied from 7.8-9.8 mg g(-1). The threshold of release of histamine from basophil leukocytes provoked by the bulk dust was between 0.3 and 1.0 mg ml(-1). The water content was 2% (WGT) and the organic fraction 33%, 6.5-5.9% (dry) was water soluble. The fiber content was less than 0.2-1.5% (WGT) and the desorbable VOCs was 176-319 mu g g(-1). Most of the VOC were aldehydes, However, softeners for plastic (DBP and DEHP) were present. The chemical composition includes human and animal skin fragments, paper fibers, glass wool, wood and textilefibers and inorganic and metal particles. The sizes ranged from 0.001-1 mm and the average specific density was 1.0 g m(-3). The bulk dust was resuspended and injected into an exposure chamber. The airborne dust was sampled and analyzed to illustrate the exposures that can result from sedimented dirt and dust. The airborne dust resulting from the bulk dust reached concentrations ranging from 0.26-0.75 mg m(-3) in average contained 300-170 CFU m(-3). The organic fraction was from 55-70% and the water content about 2.5% (WGT). The content of the dust was compared to the similar results reported in the literature and its toxic potency is estimated to be relatively low. The storage of the bulk dust during the experiment had little effect on the specific biological and chemical composition. (C) 2000 Elsevier Science Ltd. All rights reserved.