Why do we sleep?
Why do we sleep?
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DOI：
10.1016/s0006-8993(00)03007-9
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发表时间：
2000-12-15
期刊：
影响因子：
2.9
通讯作者：
Destexhe, A
中科院分区：
文献类型：
--
作者：
Sejnowski, TJ;Destexhe, A
慢波睡眠包括缓慢重复的波，这些波与跨新皮层的大规模时空同步有关。这些慢波复合体与快速振荡的短暂事件交替出现，类似于在唤醒状态期间发生的持续快速振荡。我们认为，交替的快波和慢波巩固了先前在清醒状态下获得的信息。因此，慢波睡眠开始于纺锤波振荡，开启了可塑性的分子之门，然后通过反复地“回忆”和“储存”在神经组件中启动的信息来进行。这种情况提供了一种生物物理机制，与越来越多的证据相一致，即睡眠有助于巩固记忆。(C)2000 Elsevier Science B.V.保留所有权利。
Slow-wave sleep consists in slowly recurring waves that are associated with a large-scale spatio-temporal synchrony across neocortex. These slow-wave complexes alternate with brief episodes of fast oscillations, similar to the sustained fast oscillations that occur during the wake state. We propose that alternating fast and slow waves consolidate information acquired previously during wakefulness. Slow-wave sleep would thus begin with spindle oscillations that open molecular gates to plasticity, then proceed by iteratively 'recalling' and 'storing' information primed in neural assemblies. This scenario provides a biophysical mechanism consistent with the growing evidence that sleep serves to consolidate memories. (C) 2000 Elsevier Science B.V. All rights reserved.