Catecholamines: The Effects of Maternal Fear and Its Treatment on Uterine Function and Circulation

Catecholamines: The Effects of Maternal Fear and Its Treatment on Uterine Function and Circulation
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儿茶酚胺:母亲恐惧的影响及其对子宫功能和循环的治疗

DOI:
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发表时间:
1979
期刊:
影响因子:
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通讯作者:
S. Shnider
S. Shnider
中科院分区:
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文献类型:
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作者:
G. Levinson;S. Shnider

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摘要:儿茶酚胺、肾上腺素和去甲肾上腺素引起特征性的“战或逃”反应,即心率和血压增加、血管收缩和其他自主反应。在动物研究中,注射儿茶酚胺或惊吓引起这些激素的分泌导致子宫血流量降低和胎儿心动过缓或酸中毒。 怀孕的人类母亲宫缩较弱,分娩时间较长,循环中的儿茶酚胺水平较高。在子宫循环较低的情况下,正常的胎儿可以通过提取所需的氧气来补偿,而先前受损的胎儿则不太能够补偿减少的血液供应。
ABSTRACT: Catecholamines, epinephrine and norepinephrine, cause characteristic “fight or flight” responses of increased heart rate and blood pressure, vasoconstriction, and other autonomic responses. In animal studies, either injection of Catecholamines or fright causing secretion of these hormones resulted in lower uterine blood flow and fetal bradycardia or acidosis. Anxious human mothers had weaker contractions and longer labors and higher circulating catecholamine levels. In the presence of lower uterine circulation the normal fetus may compensate by extracting the oxygen needed, while the previously compromised fetus is less able to compensate for the reduced blood supply.