Three-dimensional MRI-linac intra-fraction guidance using multiple orthogonal cine-MRI planes
Three-dimensional MRI-linac intra-fraction guidance using multiple orthogonal cine-MRI planes
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DOI：
10.1088/0031-9155/58/14/4943
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发表时间：
2013-07-21
影响因子：
3.5
通讯作者：
Keall, Paul
中科院分区：
文献类型：
--
作者：
Bjerre, Troels;Crijns, Sjoerd;Keall, Paul
集成MRI放射治疗系统的引入将提供实时部分内成像。我们提出了一种可行的低延迟多平面MRI直线加速器引导策略。在这项工作中，我们演示了如何交错采集，正交电影MRI平面可用于低延迟跟踪的软组织目标结构的三维轨迹。所提出的策略依赖于获取治疗前的3D屏气扫描，提取3D目标模板，并在该3D模板和与目标运动路径相交的正交2D电影-MRI平面对之间进行模板匹配，对于60 s的自由呼吸系列正交电影-MRI平面，我们证明了该方法能够准确地跟踪左肾的呼吸相关的3D运动。使用为此目的设计的数据集的方法的定量评价显示了1.15 mm的平移误差为39.9 mm的平移。我们已经证明了如何交错收购，正交电影MRI平面可用于软组织靶体积的在线跟踪。
The introduction of integrated MRI-radiation therapy systems will offer live intra-fraction imaging. We propose a feasible low-latency multi-plane MRI-linac guidance strategy. In this work we demonstrate how interleaved acquired, orthogonal cine-MRI planes can be used for low-latency tracking of the 3D trajectory of a soft-tissue target structure. The proposed strategy relies on acquiring a pre-treatment 3D breath-hold scan, extracting a 3D target template and performing template matching between this 3D template and pairs of orthogonal 2D cine-MRI planes intersecting the target motion path. For a 60 s free-breathing series of orthogonal cine-MRI planes, we demonstrate that the method was capable of accurately tracking the respiration related 3D motion of the left kidney. Quantitative evaluation of the method using a dataset designed for this purpose revealed a translational error of 1.15 mm for a translation of 39.9 mm. We have demonstrated how interleaved acquired, orthogonal cine-MRI planes can be used for online tracking of soft-tissue target volumes.