Validation of parental recall questionnaire to classify preterm delivery subtypes: Spontaneous preterm labour, preterm premature rupture of membranes and clinician-initiated preterm delivery.
Validation of parental recall questionnaire to classify preterm delivery subtypes: Spontaneous preterm labour, preterm premature rupture of membranes and clinician-initiated preterm delivery.
复制标题
验证父母回忆问卷对早产亚型进行分类：自发早产、早产胎膜早破和临床医生发起的早产。
DOI：
10.1111/ppe.13009
复制
发表时间：
2023
影响因子：
2.8
通讯作者：
Gray,KathrynJ
中科院分区：
文献类型：
--
作者：
Rich-Edwards,JanetW;Stuart,JenniferJ;Becene,IrisA;Largier,LouiseF;Rexrode,KathrynM;Cantonwine,DavidE;Carpenter,MaribelO;McElrath,ThomasF;Gray,KathrynJ
背景早产（PTD）包括三种主要的表现亚型：自发性早产（sPTL）、早产胎膜早破（pPROM）和临床医生发起的早产（ciPTD）。 PTD 亚型数据很少能从出生登记处获得，而且从病历中获取也很繁琐。 目的 开发并测试一份调查问卷的有效性，以根据出生父母对分娩和分娩事件的回忆对 PTD 亚型进行分类。 方法 该调查问卷于 2022 年发送给 LIFECODES 研究（马萨诸塞州波士顿医院出生队列研究）中记录的 581 名有 PTD 病史的患者。 82 名受访者报告了 94 条可能与医疗记录相关的 PTD。 PTD 亚型数据从医疗记录中提取，作为参考标准。结果医疗记录显示，47 例自发分娩（24 例 sPTL，23 例 pPROM）和 47 例 ciPTD 分娩发生时间中位数为八年前。 sPTL 回忆问卷的敏感性和特异性分别为 88%（95% 置信区间：68、97%）和 89%（79、95%）； pPROM 为 96% (78, 100%) 和 94% (86, 98%)； ciPTD 分别为 83%（69%、92%）和 100%（92%、100%）。怀孕后的时间较长并不会降低父母回忆问卷的敏感性或特异性。结论虽然来自适度的样本，但父母回忆问卷对 sPTL、pPROM 和 ciPTD 进行分类的中等到高敏感性和特异性表明了其用于大规模 PTD 研究和纠正错误分类偏倚的潜力。未来的研究需要在不同人群中测试问卷。
BackgroundPreterm delivery (PTD) includes three main presenting subtypes: spontaneous preterm labour (sPTL), preterm premature rupture of membranes (pPROM) and clinician‐initiated preterm delivery (ciPTD). PTD subtype data are rarely available from birth registries and are onerous to derive from medical records.ObjectivesTo develop and test the validity of a questionnaire to classify PTD subtype based on birthing parent recall of labour and delivery events.MethodsThe questionnaire was sent in 2022 to 581 patients with PTD history documented in the LIFECODES study, a hospital‐based birth cohort in Boston, Massachusetts. Eighty‐two respondents reported 94 PTDs that could be linked to medical records. Data on PTD subtype were extracted from medical records as the reference standard.ResultsMedical records indicated 47 spontaneous (24 sPTL, 23 pPROM) and 47 ciPTD deliveries occurring a median eight years earlier. The sensitivity and specificity of the recall questionnaire were 88% (95% confidence interval: 68, 97%) and 89% (79, 95%) for sPTL; 96% (78, 100%) and 94% (86, 98%) for pPROM; and 83% (69, 92%) and 100% (92, 100%) for ciPTD, respectively. Greater time since pregnancy did not degrade the sensitivity or specificity of the parental recall questionnaire.ConclusionsAlthough derived from a modest sample, the moderate‐to‐high sensitivity and specificity of the parental recall questionnaire to classify sPTL, pPROM and ciPTD demonstrates its potential for large studies of PTD and for correction of misclassification bias. Future studies are required to test the questionnaire in a variety of populations.