Kawasaki Disease and Multisystem Inflammatory Syndrome in Children: Common Inflammatory Pathways of Two Distinct Diseases.
Kawasaki Disease and Multisystem Inflammatory Syndrome in Children: Common Inflammatory Pathways of Two Distinct Diseases.
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DOI：
10.1016/j.rdc.2023.03.002
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发表时间：
2023-08
影响因子：
2.3
通讯作者：
Arditi, Moshe
中科院分区：
文献类型：
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作者：
Rivas, Magali Noval;Arditi, Moshe
关键词：
儿童多系统炎症综合征（MIS-C）是一种迟发性炎症后疾病，与既往严重急性呼吸道综合征冠状病毒2型（SARS-CoV-2）感染有关。最初，MIS-C被描述为与川崎病（KD）高度相似，川崎病是一种可导致冠状动脉瘤（CAA）发展的小儿发热性全身性血管炎。虽然KD和MIS-C都是炎症性疾病，但这两种疾病在流行病学、临床、免疫学和病理学特征方面存在差异。MIS-C的临床和实验室特征与中毒性休克综合征（TSS）的关系比KD更密切，这有助于了解发病机制和潜在的治疗方法。
Multisystem inflammatory syndrome in children (MIS-C) is a delayed postinflammatory disorder associated with the previous infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Initially, MIS-C was described as highly similar to Kawasaki disease (KD), a pediatric febrile systemic vasculitis that can lead to the development of coronary artery aneurysms (CAAs). While KD and MIS-C are both inflammatory disorders, the 2 entities differ in their epidemiological, clinical, immunological, and pathological features. MIS-C clinical and laboratory characteristics are more closely related to toxic shock syndrome (TSS) than KD, which informs the understanding of pathogenesis and potential therapeutic approaches.
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影响因子：
7.3
作者：
Conway SR;Lazarski CA;Field NE;Jensen-Wachspress M;Lang H;Kankate V;Durkee-Shock J;Kinoshita H;Suslovic W;Webber K;Smith K;Cohen JI;Burbelo PD;Zhang A;Teach SJ;Ibeh T;Delaney M;DeBiasi RL;Keller MD;Bollard CM
通讯作者：
Bollard CM
影响因子：
15.1
作者：
Duarte-Neto AN;Caldini EG;Gomes-Gouvêa MS;Kanamura CT;de Almeida Monteiro RA;Ferranti JF;Ventura AMC;Regalio FA;Fiorenzano DM;Gibelli MABC;Carvalho WB;Leal GN;Pinho JRR;Delgado AF;Carneiro-Sampaio M;Mauad T;Ferraz da Silva LF;Saldiva PHN;Dolhnikoff M
通讯作者：
Dolhnikoff M
影响因子：
0.7
作者：
Advani N;Sastroasmoro S;Ontoseno T;Uiterwaal CS
通讯作者：
Uiterwaal CS
影响因子：
15.9
作者：
Esteve-Sole, Ana;Anton, Jordi;Alsina, Laia
通讯作者：
Alsina, Laia
DOI：
10.1056/nejmra2206573
发表时间：
2022-09-15
期刊：
The New England journal of medicine
影响因子：
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作者：
通讯作者：
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