Risk of postpartum depression in relation to dietary fish and fat intake in Japan: the Osaka Maternal and Child Health Study
Risk of postpartum depression in relation to dietary fish and fat intake in Japan: the Osaka Maternal and Child Health Study
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DOI：
10.1017/s0033291706008701
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发表时间：
2006-12-01
影响因子：
6.9
通讯作者：
Kiyohara, Chikako
中科院分区：
文献类型：
--
作者：
Miyake, Yoshihiro;Sasaki, Satoshi;Kiyohara, Chikako
背景一项生态学分析发现，母乳中二十二碳六烯酸含量和海鲜摄入量与产后抑郁症呈负相关。这项前瞻性研究调查了选择性高脂肪食物和特定类型脂肪酸的消费与产后抑郁症风险的关系。研究对象为865名日本女性。饮食数据来自怀孕期间的自我管理饮食史问卷。采用爱丁堡产后抑郁量表（EPDS）对产后抑郁进行评定。对年龄、妊娠、产次、吸烟、家庭结构、家庭收入、教育程度、前一个月饮食变化、基线数据收集季节、体重指数、第二次调查前分娩时间、妊娠期医疗问题、婴儿性别和婴儿出生体重进行调整。抑郁得分高的女性比例为14（.）百分之零。在鱼、肉、蛋、乳制品、总脂肪、饱和脂肪酸、单不饱和脂肪酸、n-3多不饱和脂肪酸、n-6多不饱和脂肪酸、亚油酸、α-亚麻酸、花生四烯酸、二十碳五烯酸或二十二碳六烯酸的摄入量以及n-3与n-6多不饱和脂肪酸的比例与产后抑郁症的风险之间未观察到明显的剂量反应相关性。然而，n-3多不饱和脂肪酸和二十二碳六烯酸的摄入量与产后抑郁症的风险呈倒J型关系。这项研究未能证实鱼类和n-3多不饱和脂肪酸摄入量与产后抑郁症之间存在明显的负相关关系。还需要进一步的研究来确定食用鱼和n-3多不饱和脂肪酸是否可以预防产后抑郁症。
Background. An ecological analysis found that the docosahexacnoic acid content in mother's milk and seafood intake were inversely correlated with postpartum depression. This prospective study investigated the relationship of consumption of selected high-fat foods and specific types of fatty acids with the risk of Postpartum depression.Method. The subjects were 865 Japanese women. Dietary data were obtained from a self-administered diet history questionnaire during pregnancy. The Edinburgh Postnatal Depression Scale (EPDS) Was used for the evaluation of postpartum depression. Adjustment was made for age, gestation, parity, cigarette smoking, Family structure, family income, education, changes in diet in the previous month, season when data at baseline were collected, body mass index, time of delivery before the second survey, medical problems in pregnancy, baby's sex and baby's birthweight.Results. The percentage of women with high depression scores was 14(.)0%. No evident dose-response associations were observed between intake of fish, meat, eggs, dairy products, total fat, saturated fatty acids, monounsaturated fatty acids, n-3 polyunsaturated fatty acids, n-6 polyunsaturated fatty acids, linoleic acid, alpha-linolenic acid, arachidonic acid, eicosapentaenoic acid or docosahexacnoic acid and the ratio of n-3 to n-6 polyunsaturated fatty acids and the risk of postpartum depression. However, there was an inverted J-shaped relationship between intake of n-3 polyunsaturated fatty acids and docosahexacnoic acid and the risk of postpartum depression.Conclusions. This study failed to substantiate a clear inverse relationship between fish and n-3 polyunsaturated fatty acid intake and postpartum depression. Further investigations are needed to determine whether fish and n-3 polyunsaturated fatty acid consumption is preventive against postpartum depression.