Characterization of the Aspergillus nidulans nmrA gene involved in nitrogen metabolite repression

Characterization of the Aspergillus nidulans nmrA gene involved in nitrogen metabolite repression
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DOI:
10.1128/jb.180.7.1973-1977.1998
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发表时间:
1998-04-01
影响因子:
3.2
通讯作者:
Hynes, MJ
Hynes, MJ
中科院分区:
生物学3区
文献类型:
--
作者:
Andrianopoulos, A;Kourambas, S;Hynes, MJ

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构巢曲霉的nmrA基因已被分离,并发现是粗糙脉孢菌nmr-1基因的同源物,参与氮代谢物阻遏。nmrA的缺失导致受氮抑制的活性的部分去抑制,类似于在正作用areA基因中的某些突变所观察到的表型。
The gene nmrA of Aspergillus nidulans has been isolated and found to be a homolog of the Neurospora crassa gene nmr-1, involved in nitrogen metabolite repression. Deletion of nmrA results in partial derepression of activities subject to nitrogen repression similar to phenotypes observed for certain mutations in the positively acting areA gene.