Radionuclide regurgitant index: value and limitations.
Radionuclide regurgitant index: value and limitations.
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放射性核素回流指数：价值和局限性。
DOI：
10.1016/0002-9149(81)90400-8
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发表时间：
1981
期刊：
影响因子：
--
通讯作者：
K. Rosen
中科院分区：
文献类型：
--
作者：
W. Lam;D. Pavel;E. Byrom;A. Sheikh;D. Best;K. Rosen
据报道，放射性核素反流指数（定义为从门控平衡研究获得的左心室/右心室卒中计数）可以预测左侧瓣膜反流的存在和严重程度。本研究评估了 100 名患者的放射性核素反流指数，其中左侧瓣膜反流根据最严重的二尖瓣或主动脉反流进行血管造影分级（0 至 4+）。 100 名患者中，44 名患者的返流分级为 0，1+ 22 名，2+ 8 名，3+ 6 名，4+ 20 名。放射性核素返流指数为 51 名患者 0.9 至 1.5，23 名患者 1.6 至 2.4，26 名患者 2.5 至 12.0。无反流组的指数为 1.34，1+ 组的指数为 1.60，2+ 组的指数为 2.01，3+ 组的指数为 2.80，4+ 反流组的指数为 3.85。无反流患者与各反流组之间以及由两个或多个血管造影反流级别分隔的反流组之间的放射性核素反流指数存在显着差异（p <0.05）。 12 名患者的放射性核素反流指数不一致；当他们没有或轻微反流时，他们的指数预测临床显着或严重反流，或者当他们有临床显着反流时预测无或轻微反流。左心室射血分数低于 0.30 的 10 名患者中有 8 名的指数不一致 (p < 0.0005)。所有三名患有二尖瓣脱垂并伴有频繁室性早搏的患者的指数不一致（p <0.0005）。
The radionuclide regurgitant index, defined as left ventricular/right ventricular stroke counts obtained from gated equilibrium studies, has been reported to predict the presence and severity of left-sided valve regurgitation. This study evaluated the radionuclide regurgitant index in 100 patients in whom left-sided valve regurgitation was angiographically graded (0 to 4+) with regard to most severe mitral or aortic regurgitation. Regurgitation was graded 0 in 44 of the 100 patients, 1+ in 22, 2+ in 8, 3+ in 6 and 4+ in 20.The radionuclide regurgitant index was 0.9 to 1.5 in 51 patients, 1.6 to 2.4 in 23 and 2.5 to 12.0 in 26. The mean radionuclide regurgitant index was 1.34 in the group with no regurgitation and 1.60 in those with 1+, 2.01 in those with 2+, 2.80 in those with 3+ and 3.85 in those with 4+ regurgitation. There was a significant difference (p <0.05) in the radionuclide regurgitant index between patients with no regurgitation and each group with regurgitation and between groups with regurgitation separated by two or more grades of angiographic regurgitation.Twelve patients had a discordant radionuclide regurgitant index; their index either predicted clinically significant or severe regurgitation when they had no or trivial regurgitation, or predicted no or trivial regurgitation when they had clinically significant regurgitation. Eight of 10 patients with a left ventricular ejection fraction of less than 0.30 had a discordant index (p < 0.0005). All three patients with mitral valve prolapse associated with frequent ventricular extrasystoles had a discordant index (p <0.0005).