Origin and diversification of land plant CC-type glutaredoxins.
Origin and diversification of land plant CC-type glutaredoxins.
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DOI：
10.1093/gbe/evp025
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发表时间：
2009-07-31
影响因子：
3.3
通讯作者：
Zachgo S
中科院分区：
文献类型：
--
作者：
Ziemann M;Bhave M;Zachgo S
谷氧还蛋白 (GRX) 是普遍存在的谷胱甘肽依赖性氧化还原酶，参与氧化还原稳态，特别是氧化应激反应。 GRX 基因存在三个主要类别，CPYC、CGFS 类别存在于所有原核生物和真核生物物种中，而 CC 型类别 GRX 是陆地植物特有的。在陆生植物小立碗藓 (Physcomitrella patens) 中，仅存在 2 个 CC 型 GRX，而拟南芥中有 21 个。相比之下，CPYC 和 CGFS 类的大小在整个植物进化过程中保持相当相似，这提出了一个有趣的问题：CC 型 GRX 首次起源于何时以及它们在陆地植物进化过程中如何以及为何扩展。最近的证据表明，CC 型 GRX 可能在进化过程中被招募，形成多种植物特有的花发育功能（ROXY1、ROXY2）和发病反应（ROXY19/GRX480）。在本研究中，从一系列绿藻和进化多样化的陆地植物物种的基因组中鉴定出了 GRX 基因；骨球菌属、微胞菌属、团藻属、卷柏属、葡萄属、高粱属和短柄草属。整合先前鉴定的衣藻属、立碗藻属、稻属、拟南芥属和杨属植物的序列，以更全面地了解各种 GRX 类别进化背后的力量。分析表明，CC 型 GRX 可能是由于 CPYC 类的多样化而产生的，当时与植物在陆地上的殖民时期同时发生。 CC型类别的这种强烈差异扩张仅发生在被子植物中，主要是通过单子叶-真双子叶分裂后不久的古多倍体重复事件，以及最近通过在五个研究的被子植物谱系中独立发生的多个串联重复。所提供的数据表明，重复、亚功能化和随后的新功能化可能促进了陆地植物特异性 CC 型 GRX 的隔离，形成新的功能，例如发育和发病机制反应。
Glutaredoxins (GRXs) are ubiquitous glutathione-dependent oxidoreductase enzymes implicated in redox homeostasis, particularly oxidative stress response. Three major classes of GRX genes exist, the CPYC, CGFS classes are present in all pro- and eukaryote species, whereas the CC-type class GRXs are specific to land plants. In the basal land plant Physcomitrella patens, only two CC-type GRXs are present, compared with 21 in Arabidopsis. In contrast, sizes of the CPYC and CGFS classes remained rather similar throughout plant evolution, raising the interesting question as to when the CC-type GRXs first originated and how and why they expanded during land plant evolution. Recent evidence suggests that CC-type GRXs may have been recruited during evolution into diverse plant-specific functions of flower development (ROXY1, ROXY2) and pathogenesis response (ROXY19/GRX480). In the present study, GRX genes from the genomes of a range of green algae and evolutionarily diverse land plant species were identified; Ostreococcus, Micromonas, Volvox, Selaginella, Vitis, Sorghum, and Brachypodium. Previously identified sequences from Chlamydomonas, Physcomitrella, Oryza, Arabidopsis, and Populus were integrated to generate a more comprehensive understanding of the forces behind the evolution of various GRX classes. The analysis indicates that the CC-type GRXs probably arose by diversification from the CPYC class, at a time coinciding with colonization of land by plants. This strong differential expansion of the CC-type class occurred exclusively in the angiosperms, mainly through paleopolyploidy duplication events shortly after the monocot–eudicot split, and more recently through multiple tandem duplications that occurred independently in five investigated angiosperm lineages. The presented data suggest that following duplications, subfunctionalization, and subsequent neofunctionalization likely facilitated the sequestration of land plant-specific CC-type GRXs into novel functions such as development and pathogenesis response.
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影响因子：
14.9
作者：
Heazlewood, Joshua L.;Verboom, Robert E.;Millar, A. Harvey
通讯作者：
Millar, A. Harvey
DOI：
10.1093/bioinformatics/8.3.275
发表时间：
1992-06-01
期刊：
COMPUTER APPLICATIONS IN THE BIOSCIENCES
影响因子：
--
作者：
JONES, DT;TAYLOR, WR;THORNTON, JM
通讯作者：
THORNTON, JM
影响因子：
6.9
作者：
Bolwell, GP;Bindschedler, LV;Minibayeva, F
通讯作者：
Minibayeva, F
影响因子：
11.6
作者：
Li, Shutian;Lauri, Andrea;Zachgo, Sabine
通讯作者：
Zachgo, Sabine
DOI：
10.1073/pnas.0501102102
发表时间：
2005-04-12
影响因子：
11.1
作者：
Maere, S;De Bodt, S;Van de Peer, Y
通讯作者：
Van de Peer, Y