Prevalence of Helicobacter pylori in a First Nations population in northwestern Ontario.

Prevalence of Helicobacter pylori in a First Nations population in northwestern Ontario.
复制标题

安大略省西北部原住民人群中幽门螺杆菌的患病率。

DOI：
--
复制
发表时间：
2013
期刊：
Canadian family physician Medecin de famille canadien
影响因子：
--
通讯作者：
W. Hopman
W. Hopman
中科院分区：
--
文献类型：
--
作者：
A. Sethi;Monica Chaudhuri;L. Kelly;W. Hopman

文献摘要

被引文献

相似文献

客观化 评估2009至2011年间在安大略省西北部有症状的原住民人群中幽门螺杆菌感染的患病率、转诊胃镜检查的原因以及胃镜检查的临床结果。 设计 回顾了2009年6月至2011年3月期间接受上消化道内窥镜检查的304名有症状的患者的医院病历。 设置 安大略省苏瞭望的梅诺·雅温健康中心。 参与者 首批接受胃镜检查的消化不良患者。 主要结果衡量标准 转诊的原因，以及胃镜检查的临床和组织学结果。 结果 转诊胃镜检查的最常见原因是消化不良(59.2%)和未确诊的贫血(18.1%)。总体而言，66.8%的患者接受了活组织检查；其中37.9%的患者幽门螺杆菌检测呈阳性。最常见的是胃炎，占46.1%，胃溃疡占6.9%，正常胃粘膜占36.8%。幽门螺杆菌感染率高于加拿大城市人口，但低于之前的土著流行率估计，特别是基于血清阳性率的估计。 结论 这项研究提出了一个临床问题，即在疾病患病率较高的偏远地区应该如何处理根除检测和治疗方案。随着人们对幽门螺杆菌感染在严重胃肠道疾病中的作用有了更多的了解，农村和土著人口可能需要特别关注测试可获得性和离家近距离的治疗。
OBJECTIVE To assess prevalence of Helicobacter pylori infection, reasons for referral for gastroscopy, and clinical findings of gastroscopy in a symptomatic First Nations population in northwestern Ontario from 2009 to 2011. DESIGN Three hundred four hospital charts of symptomatic patients who underwent upper endoscopy between June 2009 and March 2011 were reviewed. SETTING Meno Ya Win Health Centre in Sioux Lookout, Ont. PARTICIPANTS First Nations patients with dyspepsia undergoing gastroscopy. MAIN OUTCOME MEASURES Reason for referral, and clinical and histologic findings on gastroscopy. RESULTS The most common reasons for referral for gastroscopy were dyspepsia (59.2%) and undiagnosed anemia (18.1%). Overall, 66.8% of patients underwent biopsies; 37.9% of these patients tested positive for H pylori. Gastritis was encountered the most often, in 46.1% of patients; gastric ulcers in 6.9% of patients; and normal gastric mucosa was seen 36.8% of the time. The rate of H pylori infection is higher than in urban Canadian populations, but lower than in previous aboriginal prevalence estimates, particularly those based on seroprevalence values. CONCLUSION This study raises the clinical question of how eradication testing and treatment protocols should be addressed in remote regions with high disease prevalence. As more is learned about the role H pylori infection plays in serious gastrointestinal diseases, rural and aboriginal populations might need a special focus on testing availability and treatment close to home.