Bronchopulmonary dysplasia - trends over three decades

Bronchopulmonary dysplasia - trends over three decades
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DOI:
10.1093/pch/18.2.86
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发表时间:
2013-02-01
影响因子:
1.9
通讯作者:
Landry, Jennifer S.
Landry, Jennifer S.
中科院分区:
医学4区
文献类型:
--
作者:
Zysman-Colman, Zofia;Tremblay, Genevieve M.;Landry, Jennifer S.

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Z Zysman-Colman,GM Tremblay,S Bandeali,JS Landry.支气管肺发育不良-三十年的趋势。儿科儿童健康2013;18(2):86-90。目的:描述支气管肺发育不良(BPD)和呼吸窘迫综合征受试者的特点,沿着的严重程度和死亡率的趋势与BPD在过去的three decades.METHODS:回顾性研究的BPD和呼吸窘迫综合征受试者出生于1980年和2008年之间,并承认蒙特利尔儿童医院(蒙特利尔,魁北克)。数据提取自医院records.Results:孕龄和出生体重与BPD的发生相关,妊娠期每增加一周,出生体重100 g与BPD的OR分别为0.77和0.89。BPD的严重程度与性别、新生儿Apgar评分及新生儿肺炎的发生有关。显着的趋势,观察到较低的死亡率,尽管较低的胎龄和出生体重,更大的产妇年龄和多个gestation.CONCLUSION:死亡率从BPD在过去的三十年中,尽管有显着的趋势,更明显的早产和出生体重较低,改善。
Z Zysman-Colman, GM Tremblay, S Bandeali, JS Landry. Bronchopulmonary dysplasia - trends over three decades. Paediatr Child Health 2013;18(2):86-90. OBJECTIVES: To describe the characteristics of bronchopulmonary dysplasia (BPD) and respiratory distress syndrome subjects, along with the trends in severity and mortality associated with BPD over the past three decades.METHODS: Retrospective study of BPD and respiratory distress syndrome subjects born between 1980 and 2008, and admitted to Montreal Children's Hospital (Montreal, Quebec). Data were abstracted from hospital records.RESULTS: Gestational age and birth weight were correlated with the occurrence of BPD with each additional week of gestation and 100 g in birth weight being associated with an OR of developing BPD of 0.77 and 0.89, respectively. BPD severity was associated with male sex, Apgar score and the occurrence of neonatal pneumonia. Significant trends were observed for lower mortality despite lower gestational age and birth weight, greater maternal age and multiple gestations.CONCLUSION: Mortality from BPD has improved over the past three decades despite significant trends toward more pronounced prematurity and lower birth weights.