Skin sympathetic nerve activity in Guillain-Barré syndrome: a microneurographic study
Skin sympathetic nerve activity in Guillain-Barré syndrome: a microneurographic study
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吉兰-巴利综合征的皮肤交感神经活动：显微神经描记研究
DOI：
10.1136/jnnp.63.4.537
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发表时间：
1997
期刊：
影响因子：
--
通讯作者：
T. Mitsuma
中科院分区：
文献类型：
--
作者：
Koji Yamamoto;G. Sobue;S. Iwase;M. Nagamatsu;T. Mano;T. Mitsuma
为了评估自主神经功能障碍，我们在急性期和缓解期对4例格林-巴- <s:1>综合征患者的皮肤交感神经活动（SSNA）进行了微神经造影研究。急性期出现自主神经症状，如窦性心动过速、手掌多汗症、高血压和体位性低血压，但在缓解期均消退。基础静息SSNA及对各种生理和精神刺激的反应均在急性期增加，缓解期基本恢复正常。在急性期和缓解期，对SSNA的汗率和血流量的反应率按比例保持恒定。这些发现表明，格林-巴-罗综合征的一些自主神经症状，特别是在急性期，是由于SSNA增加所致。
To assess autonomic dysfunction, skin sympathetic nerve activity (SSNA) of four patients with Guillain-Barré syndrome was microneurographically studied in the acute and remission phase. Autonomic symptoms such as sinus tachycardia, palmar hyperhidrosis, hypertension, and orthostatic hypotension were present in the acute phase, but all subsided during remission. Basal resting SSNA and the responses to various physical and mental stimuli were all increased in the acute phase and returned almost to normal during remission. Rate of response in sweat rate and blood flow against SSNA were kept proportionally constant during both the acute and remission phases. These findings suggest that some autonomic nerve symptoms of Guillain-Barré syndrome, particularly during the acute phase, are due to increased SSNA.