Fracture rates and risk factors for fractures in patients with spinal cord injury
Fracture rates and risk factors for fractures in patients with spinal cord injury
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DOI:
10.1038/sj.sc.3100648
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发表时间:
1998-11-01
期刊:
影响因子:
2.2
通讯作者:
Mosekilde, L
中科院分区:
文献类型:
--
作者:
Vestergaard, P;Krogh, K;Mosekilde, L
Aim: To study fracture rates and risk factors for fractures in patients with spinal cord injuries.Material and methods: A self-administered questionnaire was mailed to 646 members of the Danish Paraplegic Association and 1000 randomly selected normal controls. 438 patients (309 males, 129 females, 67.8%) and 654 controls (332 males, 322 females, 65.4%) returned the questionnaire. Median age in patients was 42, range 10-80 years, and in controls 43, range 19-93 years (2p = 0.25).Results: The crude fracture rate was 2% per year in patients and 1% per year in controls (RR = 2.0, P < 0.001), Low-energy fractures were much more prominent in patients (19.0% of all fractures) than in controls (1.4% , P < 0.001). The fracture rate did not differ before the injury but increased after the injury to a constant level from the third year and forward. Fractures of the lower extremities were more prominent in patients than controls (femurs: RR = 23.4, P < 0.001, lower legs: RR = 5.2, P < 0.001, feet/toes: RR = 2.4, P = 0.006) while fractures of the forearms (P < 0.001) and clavicles (P = 0.03) were absent among patients. Fractures were more frequent in female patients (RR = 1.6, P = 0.008) and in male patients with a family history of fractures (RR = 2.0, P = 0.004).Conclusions: Low-energy fractures especially of the lower extremities are frequent in spinal cord injury patients and especially among female patients. The forearms seem protected from fractures.